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    KLRK1 killer cell lectin-like receptor subfamily K, member 1 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 450153, updated on 4-May-2013
    Gene symbol
    KLRK1
    Gene description
    killer cell lectin-like receptor subfamily K, member 1
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Also known as
    NKG2-D
    Location :
    chromosome: 12
    Sequence :
    Chromosome: 12; NC_006479.3 (10569087..10586114, complement)
    See KLRK1 in MapViewer

    Chromosome 12 - NC_006479.3Genomic Context describing neighboring genes Neighboring gene GABA(A) receptor-associated protein like 1 Neighboring gene killer cell lectin-like receptor subfamily D, member 1 Neighboring gene NKG2-F type II integral membrane protein-like Neighboring gene killer cell lectin-like receptor subfamily C, member 3

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. Differential NKp30 inducibility in chimpanzee NK cells and conserved NK cell phenotype and function in long-term HIV-1-infected animals. Rutjens E, et al. J Immunol, 2007 Feb 1. PMID 17237420.
    2. Conservation and variation in human and common chimpanzee CD94 and NKG2 genes. Shum BP, et al. J Immunol, 2002 Jan 1. PMID 11751968.

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
    • Malaria, organism-specific biosystem (from KEGG)
      Malaria, organism-specific biosystemPlasmodium protozoa are parasites that account for malaria infection. Sporozoite forms of the parasite are injected by mosquito bites under the skin and are carried to the liver where they develop in...
    • Malaria, conserved biosystem (from KEGG)
      Malaria, conserved biosystemPlasmodium protozoa are parasites that account for malaria infection. Sporozoite forms of the parasite are injected by mosquito bites under the skin and are carried to the liver where they develop in...
    • Natural killer cell mediated cytotoxicity, organism-specific biosystem (from KEGG)
      Natural killer cell mediated cytotoxicity, organism-specific biosystemNatural killer (NK) cells are lymphocytes of the innate immune system that are involved in early defenses against both allogeneic (nonself) cells and autologous cells undergoing various forms of stre...
    • Natural killer cell mediated cytotoxicity, conserved biosystem (from KEGG)
      Natural killer cell mediated cytotoxicity, conserved biosystemNatural killer (NK) cells are lymphocytes of the innate immune system that are involved in early defenses against both allogeneic (nonself) cells and autologous cells undergoing various forms of stre...

    Markers

    Homology

    Preferred Names
    NKG2-D type II integral membrane protein
    Names
    NKG2-D type II integral membrane protein
    NK cell receptor D
    NKG2-D activating NK receptor
    NKG2-D-activating NK receptor
    killer cell lectin-like receptor subfamily K member 1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009059.1 → NP_001009059.1  NKG2-D type II integral membrane protein

      Status: PROVISIONAL

      Source sequence(s)
      AF259063
      UniProtKB/Swiss-Prot
      Q9MZ37
      Conserved Domains (2) summary
      cd03593
      Location:99 – 213
      Blast Score: 337
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
      PHA03097
      Location:47 – 214
      Blast Score: 128
      PHA03097; C-type lectin-like protein; Provisional

    RefSeqs of Annotated Genomes: Pan troglodytes Annotation Release 102

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Pan_troglodytes-2.1.4 Primary Assembly

    Genomic

    1. NC_006479.3 Reference Pan_troglodytes-2.1.4 Primary Assembly

      Range
      10569087..10586114, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    genomic AACZ03088159.1 (26927..43954) None
    mRNA AF259063.2 AAF86971.1
    mRNA AM113545.1 CAJ34533.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9MZ37.1 GenPept UniProtKB/Swiss-Prot:Q9MZ37

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

      Supplemental Content

      Table of contents

      Related information

      • BioProjects
        BioProjects related to a gene
      • BioSystems
        BioSystems
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • Genome
        Genome records having the gene annotated on corresponding genomic reference sequence.
      • HomoloGene
        Links between HomoloGene and Gene are provided by the HomoloGene group when a gene is included in a HomoloGene record.
      • Map Viewer
        These links are maintained by the Map Viewer group and are provided when a GeneID is annotated on a map for the same species.
      • Nucleotide
        Link to related Nucleotide entry
      • Probe
        Related Probe entry
      • Protein
        Link to related protein entry
      • PubChem Compound
        PubChem Compounds
      • PubChem Substance
        PubChem Substances
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • Taxonomy
        Link to related taxonomy entry
      • UniGene
        Links are provided between Gene and UniGene when both databases calculate links to the same mRNA record (gi).
      • UniSTS
        Related UniSTS records

      Links to other resources

      General information

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