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    Fer2LCH Ferritin 2 light chain homologue [ Drosophila melanogaster ]

    Gene ID: 44965, updated on 21-Jan-2012
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    Summary

    Official Symbol
    Fer2LCHprovided by Flybase
    Official Full Name
    Ferritin 2 light chain homologueprovided by Flybase
    Primary source
    FLYBASE:FBgn0015221
    Locus tag
    Dmel_CG1469
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    2LCH; anon-EST:ParkEST264; CG1469; Dmel\CG1469; Fer-H; Fer2LC; fer2lch; l(3)00035; l(3)07016; l(3)j2A3; l(3)neo60; l(3)neo63; l(3)s2083; LCH
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    Genomic context

    Location :
    99F2-99F2
    Sequence :
    Chromosome: 3R; NT_033777.2 (26213554..26216306)
    See Fer2LCH in Epigenomics, MapViewer

    Chromosome 3R - NT_033777.2Genomic Context describing neighboring genes Neighboring gene CG18404 gene product from transcript CG18404-RA Neighboring gene headcase Neighboring gene CG34300 gene product from transcript CG34300-RA Neighboring gene Ferritin 1 heavy chain homologue Neighboring gene CG42740 gene product from transcript CG42740-RA Neighboring gene CG15535 gene product from transcript CG15535-RA

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Drosophila mitoferrin is essential for male fertility: evidence for a role of mitochondrial iron metabolism during spermatogenesis. Metzendorf C, et al. BMC Dev Biol, 2010 Jun 21. PMID 20565922.
    2. Fenton chemistry and oxidative stress mediate the toxicity of the beta-amyloid peptide in a Drosophila model of Alzheimer's disease. Rival T, et al. Eur J Neurosci, 2009 Apr. PMID 19519625.
    3. Overexpression of Drosophila mitoferrin in l(2)mbn cells results in dysregulation of Fer1HCH expression. Metzendorf C, et al. Biochem J, 2009 Jul 15. PMID 19453295.
    4. Hyperoxia-induced neurodegeneration as a tool to identify neuroprotective genes in Drosophila melanogaster. Gruenewald C, et al. Free Radic Biol Med, 2009 Jun 15. PMID 19345730.
    5. ER stress protects from retinal degeneration. Mendes CS, et al. EMBO J, 2009 May 6. PMID 19339992.

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:69415 BioGRID:59397 CG10918    BioGRID  PubMed Two-hybrid 
    BioGRID:69415 BioGRID:66384 CG12811    BioGRID  PubMed Two-hybrid 
    BioGRID:69415 BioGRID:61730 CG8235    BioGRID  PubMed Two-hybrid 
    BioGRID:69415 BioGRID:70219 Fer1HCH    BioGRID  PubMed Two-hybrid 
    BioGRID:69415 BioGRID:63578 Kr    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:69415 BioGRID:58911 exd    BioGRID  PubMed Two-hybrid 
    BioGRID:69415 BioGRID:66435 fau    BioGRID  PubMed Two-hybrid 
    BioGRID:69415 BioGRID:68723 prc    BioGRID  PubMed Two-hybrid 
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    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    ferric iron binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    ferrous iron binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    cellular iron ion homeostasis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    chaeta development IGI
    Inferred from Genetic Interaction
    more info
    		  
    iron ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    intracellular ferritin complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    CG1469 gene product from transcript CG1469-RA
    Names
    CG1469-PA
    CG1469-PB
    CG1469-PC
    Fer2LCH-PA
    Fer2LCH-PB
    Fer2LCH-PC
    Ferritin-Heavy
    Ferritin-Light
    ferritin
    ferritin 2 light chain homologue
    NP_524802.2
    NP_733362.1
    NP_733363.1
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.2

      Range
      26213554..26216306
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_080063.2 → NP_524802.2  ferritin 2 light chain homologue, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VA83
      Related
      FBpp0084986, FBtr0085622
      Conserved Domains (2) summary
      cd01056
      Location:51 – 223
      Blast Score: 446
      Euk_Ferritin; eukaryotic ferritins
      pfam00210
      Location:58 – 207
      Blast Score: 118
      Ferritin; Ferritin-like domain

    2. NM_170483.1 → NP_733362.1  ferritin 2 light chain homologue, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VA83
      Related
      FBpp0084987, FBtr0085623
      Conserved Domains (2) summary
      cd01056
      Location:51 – 223
      Blast Score: 446
      Euk_Ferritin; eukaryotic ferritins
      pfam00210
      Location:58 – 207
      Blast Score: 118
      Ferritin; Ferritin-like domain

    3. NM_170484.1 → NP_733363.1  ferritin 2 light chain homologue, isoform C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VA83
      Related
      FBpp0084988, FBtr0085624
      Conserved Domains (2) summary
      cd01056
      Location:51 – 223
      Blast Score: 446
      Euk_Ferritin; eukaryotic ferritins
      pfam00210
      Location:58 – 207
      Blast Score: 118
      Ferritin; Ferritin-like domain
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014297.2 AAN14228.1
    genomic AE014297.2 AAN14229.1
    mRNA AY070805.1 AAL48427.1
    genomic AE014297.2 AAF57038.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    Q9VA83.1 GenPept
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    Additional Links

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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