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bglap bone gamma-carboxyglutamate protein [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 448310, updated on 5-Mar-2024

Summary

Official Symbol
bglapprovided by Xenbase
Official Full Name
bone gamma-carboxyglutamate proteinprovided by Xenbase
Primary source
Xenbase:XB-GENE-1018467
See related
Ensembl:ENSXETG00000002605
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
bgp; pmf1
Orthologs
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Genomic context

Location:
chromosome: 8
Exon count:
4
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 8 NC_030684.2 (141512944..141517197)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) Unplaced Scaffold NW_016684010.1 (25714..29969, complement)

Chromosome 8 - NC_030684.2Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 44 Neighboring gene polyamine-modulated factor 1 Neighboring gene progestin and adipoQ receptor family member VI Neighboring gene dihydroxyacetone phosphate acyltransferase Neighboring gene SMG5 nonsense mediated mRNA decay factor

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Clone Names

  • MGC89111

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables hormone activity IEA
Inferred from Electronic Annotation
more info
 
enables hormone activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables hydroxyapatite binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of bone IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of bone ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within biomineral tissue development IEA
Inferred from Electronic Annotation
more info
 
involved_in bone development IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within bone development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cellular response to insulin stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within glucose homeostasis ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within negative regulation of bone development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in osteoblast differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of bone mineralization IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within response to vitamin K IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within type B pancreatic cell proliferation ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
is_active_in extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
osteocalcin
Names
bone Gla protein
bone gamma-carboxyglutamate (gla) protein (osteocalcin)
gamma-carboxyglutamic acid-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001006688.1NP_001006689.1  osteocalcin precursor

    See identical proteins and their annotated locations for NP_001006689.1

    Status: PROVISIONAL

    Source sequence(s)
    BC075385
    UniProtKB/Swiss-Prot
    Q6DJ00
    UniProtKB/TrEMBL
    A0A1B8XWL8
    Related
    ENSXETP00000005554.4, ENSXETT00000005554.5
    Conserved Domains (1) summary
    cl02449
    Location:3598
    Gla; Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    141512944..141517197
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)