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cul3.L cullin 3 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 446487, updated on 11-Apr-2024

Summary

Official Symbol
cul3.L
Official Full Name
cullin 3 L homeolog
Primary source
Xenbase:XB-GENE-974989
Locus tag
XELAEV_18027771mg
See related
EnsemblRapid:ENSXLAG00005017109
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
cul3; cul3a; cul3-a; cul3-b; CUL-3-A; Cullin-3-A
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Genomic context

Location:
chromosome: 5L
Exon count:
16
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5L NC_054379.1 (132363524..132411969)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5L NC_030732.1 (121606016..121655083)

Chromosome 5L - NC_054379.1Genomic Context describing neighboring genes Neighboring gene splA/ryanodine receptor domain and SOCS box containing 4 L homeolog Neighboring gene 2-phosphoxylose phosphatase 1 L homeolog Neighboring gene putative serine protease K12H4.7 Neighboring gene family with sequence similarity 124 member B L homeolog

Genomic regions, transcripts, and products

General gene information

Clone Names

  • MGC79108

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to ubiquitin-protein transferase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within COPII vesicle coating ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell migration ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within embryonic cleavage ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within endoplasmic reticulum to Golgi vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within integrin-mediated signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within mitotic metaphase chromosome alignment ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within negative regulation of Rho protein signal transduction ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within positive regulation of mitotic cell cycle phase transition ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within positive regulation of mitotic metaphase/anaphase transition ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within proteasome-mediated ubiquitin-dependent protein catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within protein monoubiquitination ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within protein ubiquitination ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within stem cell division ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within stress fiber assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of Cul3-RING ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
 
part_of Cul3-RING ubiquitin ligase complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in centrosome ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of cullin-RING ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
 
located_in mitotic spindle ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in polar microtubule ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in spindle pole ISS
Inferred from Sequence or Structural Similarity
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093183.1NP_001086652.1  cullin-3-A

    See identical proteins and their annotated locations for NP_001086652.1

    Status: PROVISIONAL

    Source sequence(s)
    BC077239
    UniProtKB/Swiss-Prot
    Q6DE95
    UniProtKB/TrEMBL
    A0A974HK25
    Related
    ENSXLAP00005050479.1, ENSXLAT00005051620.1
    Conserved Domains (3) summary
    smart00182
    Location:421563
    CULLIN; Cullin
    pfam00888
    Location:35664
    Cullin; Cullin family
    pfam10557
    Location:700760
    Cullin_Nedd8; Cullin protein neddylation domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    132363524..132411969
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018261936.2XP_018117425.1  cullin-3-A isoform X1

    UniProtKB/Swiss-Prot
    Q6DE95
    UniProtKB/TrEMBL
    A0A974HK25
  2. XM_018261937.2XP_018117426.1  cullin-3-A isoform X2

    UniProtKB/TrEMBL
    A0A8J0V8F3