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elac1 elaC ribonuclease Z 1 [ Danio rerio (zebrafish) ]

Gene ID: 445109, updated on 27-Mar-2024

Summary

Official Symbol
elac1provided by ZNC
Official Full Name
elaC ribonuclease Z 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040801-246
See related
Ensembl:ENSDARG00000045095 AllianceGenome:ZFIN:ZDB-GENE-040801-246
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:91956
Summary
Predicted to enable 3'-tRNA processing endoribonuclease activity. Predicted to act upstream of or within tRNA 3'-trailer cleavage. Predicted to be active in nucleus. Orthologous to human ELAC1 (elaC ribonuclease Z 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 5
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (6854454..6864127)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (6291980..6301560)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene amphiregulin Neighboring gene malic enzyme 2, NAD(+)-dependent, mitochondrial Neighboring gene SMAD family member 4b Neighboring gene mex-3 RNA binding family member C

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables 3'-tRNA processing endoribonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables 3'-tRNA processing endoribonuclease activity IEA
Inferred from Electronic Annotation
more info
 
enables RNA endonuclease activity, producing 5'-phosphomonoesters IEA
Inferred from Electronic Annotation
more info
 
enables endonuclease activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nuclease activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within tRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
zinc phosphodiesterase ELAC protein 1
Names
elaC homolog 1
NP_001003503.1
XP_021331758.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003503.1NP_001003503.1  zinc phosphodiesterase ELAC protein 1

    See identical proteins and their annotated locations for NP_001003503.1

    Status: PROVISIONAL

    Source sequence(s)
    BC078352
    UniProtKB/TrEMBL
    Q6DBV0
    Related
    ENSDARP00000066306.4, ENSDART00000066307.6
    Conserved Domains (2) summary
    COG1234
    Location:3364
    ElaC; Ribonuclease BN, tRNA processing enzyme [Translation, ribosomal structure and biogenesis]
    TIGR02651
    Location:4364
    RNase_Z; ribonuclease Z

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    6854454..6864127
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021476083.1XP_021331758.1  zinc phosphodiesterase ELAC protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M9PXC3
    Conserved Domains (1) summary
    TIGR02651
    Location:4395
    RNase_Z; ribonuclease Z

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394563.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    203622..213202
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)