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    EfTuM Elongation factor Tu mitochondrial [ Drosophila melanogaster ]

    Gene ID: 44438, updated on 10-May-2012
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    Summary

    Official Symbol
    EfTuMprovided by Flybase
    Official Full Name
    Elongation factor Tu mitochondrialprovided by Flybase
    Primary source
    FLYBASE:FBgn0024556
    Locus tag
    Dmel_CG6050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG6050; Dmel\CG6050; eftu-M; efTuM; l(3)L4569; mtEF-Tu
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    Genomic context

    Location :
    50A14-50A14
    Sequence :
    Chromosome: 2R; NT_033778.3 (9395063..9396837)
    See EfTuM in Epigenomics, MapViewer

    Chromosome 2R - NT_033778.3Genomic Context describing neighboring genes Neighboring gene bb in a boxcar Neighboring gene downstream of receptor kinase Neighboring gene CG17064 gene product from transcript CG17064-RB Neighboring gene Myb-interacting protein 120 Neighboring gene Vesicular monoamine transporter Neighboring gene CG13330 gene product from transcript CG13330-RA Neighboring gene CG13331 gene product from transcript CG13331-RB

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573.
    2. Identification of ER proteins involved in the functional organisation of the early secretory pathway in Drosophila cells by a targeted RNAi screen. Kondylis V, et al. PLoS One, 2011 Feb 23. PMID 21383842.
    3. Loss of the SIN3 transcriptional corepressor results in aberrant mitochondrial function. Barnes VL, et al. BMC Biochem, 2010 Jul 9. PMID 20618965.
    4. Mars, a Drosophila protein related to vertebrate HURP, is required for the attachment of centrosomes to the mitotic spindle during syncytial nuclear divisions. Zhang G, et al. J Cell Sci, 2009 Feb 15. PMID 19174464.
    5. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:69061 BioGRID:68371 ATPsyn-gamma    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:65734 Arf79F    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:64295 CG12262    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:60665 CG12264    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:59736 CG17259    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:77765 CG33303    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:65149 CG4169    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:67767 CG5854    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:62714 CG6370    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:67074 Cctgamma    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:58885 Chc    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:69179 Cnx99A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:62300 Cp1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:72482 CycK    BioGRID  PubMed Two-hybrid 
    BioGRID:69061 BioGRID:73191 Cyp12d1-p    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:68252 Gfat2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:60312 Glt    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:68235 Gp93    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:59949 Hel25E    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:66317 Kap-alpha3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:64920 Mpcp    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:64690 Pi3K68D    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:68766 Sucb    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:58868 Tcp-1zeta    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:60532 Trim9    BioGRID  PubMed Two-hybrid 
    BioGRID:69061 BioGRID:59137 betaCop    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:59242 l(1)G0156    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:58976 r    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:66236 skap    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:69061 BioGRID:62039 wal    BioGRID  PubMed Affinity Capture-MS 
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    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    translation elongation factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    Golgi organization IMP
    Inferred from Mutant Phenotype
    more info
    		  
    cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		  
    mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    		  
    translational elongation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
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    General protein information

    Preferred Names
    CG6050 gene product from transcript CG6050-RA
    Names
    CG6050-PA
    CG6050-PB
    EfTuM-PA
    EfTuM-PB
    elongation factor Tu mitochondrial
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.3

      Range
      9395063..9396837
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_080013.3 → NP_524752.1  elongation factor Tu mitochondrial, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z9E3
      Related
      FBpp0086790, FBtr0087670
      Conserved Domains (4) summary
      cd03706
      Location:371 – 451
      Blast Score: 341
      mtEFTU_III; Domain III of mitochondrial EF-TU (mtEF-TU). mtEF-TU is highly conserved and is 55-60% identical to bacterial EF-TU. The overall structure is similar to that observed in the Escherichia coli and Thermus aquaticus EF-TU. However, compared with that ...
      cd03697
      Location:282 – 368
      Blast Score: 388
      EFTU_II; EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the ...
      PRK00049
      Location:73 – 450
      Blast Score: 1677
      PRK00049; elongation factor Tu; Reviewed
      cd01884
      Location:81 – 274
      Blast Score: 1045
      EF_Tu; Elongation Factor Tu (EF-Tu) GTP-binding proteins

    2. NM_001169673.1 → NP_001163144.1  elongation factor Tu mitochondrial, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z9E3
      Related
      FBpp0290603, FBtr0301389
      Conserved Domains (4) summary
      cd03706
      Location:371 – 451
      Blast Score: 341
      mtEFTU_III; Domain III of mitochondrial EF-TU (mtEF-TU). mtEF-TU is highly conserved and is 55-60% identical to bacterial EF-TU. The overall structure is similar to that observed in the Escherichia coli and Thermus aquaticus EF-TU. However, compared with that ...
      cd03697
      Location:282 – 368
      Blast Score: 388
      EFTU_II; EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the ...
      PRK00049
      Location:73 – 450
      Blast Score: 1677
      PRK00049; elongation factor Tu; Reviewed
      cd01884
      Location:81 – 274
      Blast Score: 1045
      EF_Tu; Elongation Factor Tu (EF-Tu) GTP-binding proteins
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE013599.4 AAF58366.1
    genomic AE013599.4 AAM68586.2
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V6Q7.1 GenPept
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    Additional Links

    Gene LinkOut

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