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PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) [ Canis lupus familiaris (dog) ]

Gene ID: 442942, updated on 7-Aug-2014
Gene symbol
PTGS2
Gene description
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
See related
Ensembl:ENSCAFG00000013762
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
COX-2
See PTGS2 in MapViewer
Location:
chromosome: 7
Exon count:
11
Annotation release Status Assembly Chr Location
103 current CanFam3.1 (GCF_000002285.3) 7 NC_006589.3 (19668079..19674911, complement)

Chromosome 7 - NC_006589.3Genomic Context describing neighboring genes Neighboring gene YTH domain family protein 1-like Neighboring gene mitochondrial fission regulator 1 pseudogene Neighboring gene non-POU domain containing, octamer-binding pseudogene Neighboring gene uncharacterized LOC102153640

Genomic Sequence:
NC_006589.3 chromosome 7 reference CanFam3.1 Primary Assembly

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Preferred Names
prostaglandin G/H synthase 2
Names
prostaglandin G/H synthase 2
cyclooxygenase 2
cyclooxygenase type 2
prostaglandin G/H synthase-2
NP_001003354.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003354.1NP_001003354.1  prostaglandin G/H synthase 2 precursor

    See proteins identical to NP_001003354.1

    Status: PROVISIONAL

    Source sequence(s)
    AY044905
    UniProtKB/TrEMBL
    Q8SPQ9
    Related
    ENSCAFP00000020288, ENSCAFT00000021841
    Conserved Domains (3) summary
    cd09816
    Location:75562
    Blast Score: 2165
    prostaglandin_endoperoxide_synthase; Animal prostaglandin endoperoxide synthase and related bacterial proteins
    cd00054
    Location:1954
    Blast Score: 100
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam03098
    Location:122560
    Blast Score: 1088
    An_peroxidase; Animal haem peroxidase

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 103

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CanFam3.1 Primary Assembly

Genomic

  1. NC_006589.3 

    Range
    19668079..19674911
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005622227.1XP_005622284.1  

    See proteins identical to XP_005622284.1

    UniProtKB/TrEMBL
    Q8SPQ9
    Related
    ENSCAFP00000038440, ENSCAFT00000044614
    Conserved Domains (3) summary
    cd09816
    Location:75562
    Blast Score: 2165
    prostaglandin_endoperoxide_synthase; Animal prostaglandin endoperoxide synthase and related bacterial proteins
    cd00054
    Location:1954
    Blast Score: 100
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam03098
    Location:122560
    Blast Score: 1088
    An_peroxidase; Animal haem peroxidase
  2. XM_005622228.1XP_005622285.1  

    Conserved Domains (2) summary
    cd09816
    Location:43530
    Blast Score: 2151
    prostaglandin_endoperoxide_synthase; Animal prostaglandin endoperoxide synthase and related bacterial proteins
    pfam03098
    Location:90528
    Blast Score: 1084
    An_peroxidase; Animal haem peroxidase