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    E23 Early gene at 23 [ Drosophila melanogaster ]

    Gene ID: 43895, updated on 9-May-2012
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    Summary

    Official Symbol
    E23provided by Flybase
    Official Full Name
    Early gene at 23provided by Flybase
    Primary source
    FLYBASE:FBgn0020445
    Locus tag
    Dmel_CG3327
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15410; CG3327; Dmel\CG3327
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    Genomic context

    Location :
    23E4-23E5
    Sequence :
    Chromosome: 2L; NT_033779.4 (3334871..3355000, complement)
    See E23 in Epigenomics, MapViewer

    Chromosome 2L - NT_033779.4Genomic Context describing neighboring genes Neighboring gene CG33282 gene product from transcript CG33282-RB Neighboring gene CG3285 gene product from transcript CG3285-RA Neighboring gene CG15408 gene product from transcript CG15408-RA Neighboring gene CG8838 gene product from transcript CG8838-RA Neighboring gene CG34394 gene product from transcript CG34394-RF

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Membrane-bound transporter controls the circadian transcription of clock genes in Drosophila. Itoh TQ, et al. Genes Cells, 2011 Dec. PMID 22077638.
    2. A functional genomics strategy reveals clockwork orange as a transcriptional regulator in the Drosophila circadian clock. Matsumoto A, et al. Genes Dev, 2007 Jul 1. PMID 17578908.
    3. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.
    4. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856.
    5. The Drosophila nucleosome remodeling factor NURF is required for Ecdysteroid signaling and metamorphosis. Badenhorst P, et al. Genes Dev, 2005 Nov 1. PMID 16264191.

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. E23 forms its own feedback loop in the ecdysone response to control circadian oscillation through ecdysone-mediated vrille expression.
      Title: Membrane-bound transporter controls the circadian transcription of clock genes in Drosophila.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:68699 BioGRID:66494 KP78b    BioGRID  PubMed Two-hybrid 
    BioGRID:68699 BioGRID:67115 TwdlW    BioGRID  PubMed Two-hybrid 
    BioGRID:68699 BioGRID:62080 skpB    BioGRID  PubMed Two-hybrid 
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    General gene information

    Markers

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    ATPase activity, coupled to transmembrane movement of substances ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    ATPase activity, coupled to transmembrane movement of substances NAS
    Non-traceable Author Statement
    more info
    		  
    transporter activity NAS
    Non-traceable Author Statement
    more info
    		  
    Process Evidence Code Pubs
    regulation of circadian rhythm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    ATP-binding cassette (ABC) transporter complex NAS
    Non-traceable Author Statement
    more info
    		  
    membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Preferred Names
    CG3327 gene product from transcript CG3327-RA
    Names
    CG3327-PA
    CG3327-PB
    CG3327-PC
    E23-PA
    E23-PB
    E23-PC
    early gene at 23
    NP_524648.2
    NP_608768.1
    NP_995622.1
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.4

      Range
      3334871..3355000, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079909.2 → NP_524648.2  early gene at 23, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQP4
      Related
      FBpp0088919, FBtr0089981
      Conserved Domains (3) summary
      COG1136
      Location:199 – 404
      Blast Score: 370
      SalX; ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]
      cd03213
      Location:187 – 409
      Blast Score: 603
      ABCG_EPDR; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes ...
      cl11417
      Location:576 – 783
      Blast Score: 314
      ABC2_membrane; ABC-2 type transporter

    2. NM_205900.1 → NP_995622.1  early gene at 23, isoform C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KU30
      Related
      FBpp0088917, FBtr0089979
      Conserved Domains (3) summary
      COG1136
      Location:362 – 567
      Blast Score: 369
      SalX; ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]
      cd03213
      Location:350 – 572
      Blast Score: 603
      ABCG_EPDR; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes ...
      cl11417
      Location:739 – 946
      Blast Score: 314
      ABC2_membrane; ABC-2 type transporter

    3. NM_134924.1 → NP_608768.1  early gene at 23, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQP3
      Related
      FBpp0088918, FBtr0089980
      Conserved Domains (3) summary
      cd03213
      Location:1 – 189
      Blast Score: 530
      ABCG_EPDR; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes ...
      pfam00005
      Location:9 – 134
      Blast Score: 239
      ABC_tran; ABC transporter
      cl11417
      Location:356 – 563
      Blast Score: 308
      ABC2_membrane; ABC-2 type transporter
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014134.5 AAF51121.2
    mRNA BT133432.1 AFH68356.1
    genomic AE014134.5 AAS64617.1
    genomic AE014134.5 AAF51122.2
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VQP4.1 GenPept
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    Additional Links

    Gene LinkOut

      Supplemental Content