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    Asator [ Drosophila melanogaster ]

    Gene ID: 43794, updated on 9-May-2012
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    Summary

    Official Symbol
    Asatorprovided by Flybase
    Primary source
    FLYBASE:FBgn0039908
    Locus tag
    Dmel_CG11533
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11533; CK I; CKI-like; Dmel\CG11533
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    Genomic context

    Location :
    102C1-102C1
    Sequence :
    Chromosome: 4; NC_004353.3 (491912..504406, complement)
    See Asator in Epigenomics, MapViewer

    Chromosome 4 - NC_004353.3Genomic Context describing neighboring genes Neighboring gene Calcium/calmodulin-dependent protein kinase I Neighboring gene putative noncoding RNA 013:4 Neighboring gene CG2009 gene product from transcript CG2009-RA Neighboring gene Zn finger homeodomain 2 Neighboring gene CG1981 gene product from transcript CG1981-RA

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Asator, a tau-tubulin kinase homolog in Drosophila localizes to the mitotic spindle. Qi H, et al. Dev Dyn, 2009 Dec. PMID 19890914.
    2. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.
    3. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856.
    4. A gain-of-function screen identifying genes required for vein formation in the Drosophila melanogaster wing. Molnar C, et al. Genetics, 2006 Nov. PMID 16980395.
    5. Combined evidence annotation of transposable elements in genome sequences. Quesneville H, et al. PLoS Comput Biol, 2005 Jul. PMID 16110336.

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Asator localizes to the spindle region during mitosis and directly can interact with Megator; this suggests that its kinase activity may be involved in regulating microtubule dynamics and microtubule spindle function.
      Title: Asator, a tau-tubulin kinase homolog in Drosophila localizes to the mitotic spindle.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:68627 BioGRID:58907 CG9170    BioGRID  PubMed Two-hybrid 
    BioGRID:68627 BioGRID:68567 CycG    BioGRID  PubMed Two-hybrid 
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    General gene information

    mobile_element

    • Loc: c497025-496970 mobile_element_type = transposon:INE-1{}5932
    • Loc: c497109-497028 mobile_element_type = transposon:INE-1{}5934

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    protein serine/threonine kinase activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    protein phosphorylation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    spindle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    CG11533 gene product from transcript CG11533-RF
    Names
    Asator-PD
    Asator-PE
    Asator-PF
    CG11533-PD
    CG11533-PE
    CG11533-PF
    asator
    NP_651924.2
    NP_726576.2
    NP_726577.2
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004353.3

      Range
      491912..504406, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_166766.2 → NP_726577.2  asator, isoform F [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IMC5
      Related
      FBpp0289573, FBtr0300344
      Conserved Domains (2) summary
      cd00180
      Location:36 – 215
      Blast Score: 306
      PKc; Catalytic domain of Protein Kinases
      pfam00069
      Location:17 – 256
      Blast Score: 304
      Pkinase; Protein kinase domain

    2. NM_143667.2 → NP_651924.2  asator, isoform D [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V4D6
      Related
      FBpp0289571, FBtr0300342
      Conserved Domains (2) summary
      cd00180
      Location:192 – 371
      Blast Score: 310
      PKc; Catalytic domain of Protein Kinases
      pfam00069
      Location:173 – 412
      Blast Score: 307
      Pkinase; Protein kinase domain

    3. NM_166765.2 → NP_726576.2  asator, isoform E [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IMC6
      Related
      FBpp0289572, FBtr0300343
      Conserved Domains (2) summary
      cd00180
      Location:192 – 371
      Blast Score: 308
      PKc; Catalytic domain of Protein Kinases
      pfam00069
      Location:173 – 412
      Blast Score: 306
      Pkinase; Protein kinase domain
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014135.3 AAN06496.2
    genomic AE014135.3 AAF59340.3
    mRNA BT133187.1 AFA28428.1
    genomic AE014135.3 AAN06495.2
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    Additional Links

    Gene LinkOut

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