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    spn-F [ Drosophila melanogaster ]

    Gene ID: 43700, updated on 8-Jan-2012
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    Summary

    Official Symbol
    spn-Fprovided by Flybase
    Primary source
    FLYBASE:FBgn0086362
    Locus tag
    Dmel_CG12114
    Gene type
    protein coding
    RNA name
    spn-F
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    1130/03; CG12114; Dmel\CG12114; l(3)S113003b; Spn-F
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    Genomic context

    Location :
    100B8-100B9; 3-100 cM
    Sequence :
    Chromosome: 3R; NT_033777.2 (27080864..27082388)
    See spn-F in Epigenomics, MapViewer

    Chromosome 3R - NT_033777.2Genomic Context describing neighboring genes Neighboring gene CG31005 gene product from transcript CG31005-RA Neighboring gene mitochondrial ribosomal protein L32 Neighboring gene CG1750 gene product from transcript CG1750-RA Neighboring gene CG3669 gene product from transcript CG3669-RB Neighboring gene CG18672 gene product from transcript CG18672-RA

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Asymmetric microtubule function is an essential requirement for polarized organization of the Drosophila bristle. Bitan A, et al. Mol Cell Biol, 2010 Jan. PMID 19917727.
    2. PIP5K-dependent production of PIP2 sustains microtubule organization to establish polarized transport in the Drosophila oocyte. Gervais L, et al. Development, 2008 Dec. PMID 18948416.
    3. The Drosophila IKK-related kinase (Ik2) and Spindle-F proteins are part of a complex that regulates cytoskeleton organization during oogenesis. Dubin-Bar D, et al. BMC Cell Biol, 2008 Sep 17. PMID 18796167.
    4. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.
    5. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856.

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Spn-F and Ik2 are localized to the bristle tip and that mutations in ik2 and spn-F affect bristle microtubules and actin organization
      Title: Asymmetric microtubule function is an essential requirement for polarized organization of the Drosophila bristle.
    2. IkappaB kinase 2 binds physically to Spindle-F protein, biomolecular interaction analysis of Spindle-F protein and IkappaB kinase 2 demonstrating that both proteins bind directly and form a complex
      Title: The Drosophila IKK-related kinase (Ik2) and Spindle-F proteins are part of a complex that regulates cytoskeleton organization during oogenesis.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:68545 BioGRID:69246 Ady43A    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:64777 CG10654    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:64802 CG11006    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:58700 CG11164    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:61586 CG12107    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:68073 CG14556    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:57687 CG14815    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:68515 CG15549    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:77402 CG31523    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:66862 CG3563    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:66990 CG5478    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:61061 CG7094    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:66210 CG8116    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:66706 CG8141    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:63097 NC2alpha    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:68320 Rpn2    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:73152 Tango11    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:60464 Utx    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:63640 Vti1    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:57920 ctp    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:61890 gem    BioGRID  PubMed Two-hybrid 
    BioGRID:68545 BioGRID:61292 ik2    BioGRID  PubMed Two-hybrid 
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    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    minus-end-directed microtubule motor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    chaeta morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    oocyte axis specification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    oocyte microtubule cytoskeleton organization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    regulation of cytoskeleton organization IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    CG12114 gene product from transcript CG12114-RA
    Names
    CG12114-PA
    Spindle-F
    lethal (3) S113003b
    spindle F
    spn-F
    spn-F-PA
    NP_651858.1
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.2

      Range
      27080864..27082388
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143601.2 → NP_651858.1  spn-F [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V9Y9
      Related
      FBpp0085122, FBtr0085760
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014297.2 AAF57139.1
    mRNA AY061046.1 AAL28594.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    Q9V9Y9.1 GenPept
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    Additional Links

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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