qless [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: qlessprovided by FlyBase
Primary source: FLYBASE:FBgn0051005
Locus tag: Dmel_CG31005
See related: AllianceGenome:FB:FBgn0051005
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0118547.422; CG15565; CG31005; CG3684; Dmel\CG31005; Qless
Summary: Predicted to enable prenyltransferase activity. Predicted to contribute to trans-hexaprenyltranstransferase activity. Involved in several processes, including isoprenoid biosynthetic process; neuroblast development; and response to mitochondrial depolarisation. Predicted to be part of transferase complex. Is expressed in several structures, including presumptive embryonic/larval system. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 2. Orthologous to human PDSS1 (decaprenyl diphosphate synthase subunit 1). [provided by Alliance of Genome Resources, Apr 2022]
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (31236035..31252608, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (27061757..27078330, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables all-trans-decaprenyl-diphosphate synthase activity	ISS Inferred from Sequence or Structural Similarity more info
enables prenyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in isoprenoid biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in isoprenoid biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in isoprenoid biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of apoptotic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in neuroblast development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to mitochondrial depolarisation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in ubiquinone biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of heterotetrameric polyprenyl diphosphate synthase complex	ISS Inferred from Sequence or Structural Similarity more info
part_of transferase complex	IBA Inferred from Biological aspect of Ancestor more info

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The following sections contain reference sequences that belong to a specific genome build. Explain