Pglym78 Phosphoglyceromutase [Drosophila melanogaster] - Gene

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Summary

Official Symbol: Pglym78provided by Flybase
Official Full Name: Phosphoglyceromutaseprovided by Flybase
Primary source: FLYBASE:FBgn0014869
Locus tag: Dmel_CG1721
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG1721; Dmel\CG1721; PGAM; Pglym; PGLYM

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Genomic context

Location :: 98F12-98F13

Sequence :: Chromosome: 3R; NT_033777.2 (24973970..24975623)

See Pglym78 in Epigenomics, MapViewer

Chromosome 3R - NT_033777.2 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

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Interactions

Products	Interactant	Other Gene	Complex	Source	Pubs	Description
BioGRID:68318	BioGRID:68567	CycG		BioGRID	PubMed	Two-hybrid

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General gene information

Homology

Homologs of the Pglym78 gene: The Pglym78 gene is conserved in human, chimpanzee, dog, cow, mouse, chicken, zebrafish, and mosquito.

Pathways from BioSystems

Gluconeogenesis, organism-specific biosystem (from REACTOME)
Gluconeogenesis, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Gluconeogenesis, oxaloacetate => fructose-6P, organism-specific biosystem (from KEGG)
Gluconeogenesis, oxaloacetate => fructose-6P, organism-specific biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Gluconeogenesis, oxaloacetate => fructose-6P, conserved biosystem (from KEGG)
Gluconeogenesis, oxaloacetate => fructose-6P, conserved biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Glucose metabolism, organism-specific biosystem (from REACTOME)
Glucose metabolism, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Glycine, serine and threonine metabolism, organism-specific biosystem (from KEGG)
Glycine, serine and threonine metabolism, organism-specific biosystemSerine is derived from 3-phospho-D-glycerate, an intermediate of glycolysis [MD:M00020], and glycine is derived from serine. Threonine is an essential amino acid, which animals cannot synthesize. In ...
Glycine, serine and threonine metabolism, conserved biosystem (from KEGG)
Glycine, serine and threonine metabolism, conserved biosystemSerine is derived from 3-phospho-D-glycerate, an intermediate of glycolysis [MD:M00020], and glycine is derived from serine. Threonine is an essential amino acid, which animals cannot synthesize. In ...
Glycolysis, organism-specific biosystem (from REACTOME)
Glycolysis, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate, organism-specific biosystem (from KEGG)
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate, organism-specific biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate, conserved biosystem (from KEGG)
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate, conserved biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Glycolysis / Gluconeogenesis, organism-specific biosystem (from KEGG)
Glycolysis / Gluconeogenesis, organism-specific biosystemGlycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabol...
Glycolysis / Gluconeogenesis, conserved biosystem (from KEGG)
Glycolysis / Gluconeogenesis, conserved biosystemGlycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabol...
Glycolysis and Gluconeogenesis, organism-specific biosystem (from WikiPathways)
Glycolysis and Gluconeogenesis, organism-specific biosystem
Glycolysis and Gluconeogenesis
Glycolysis, core module involving three-carbon compounds, organism-specific biosystem (from KEGG)
Glycolysis, core module involving three-carbon compounds, organism-specific biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Glycolysis, core module involving three-carbon compounds, conserved biosystem (from KEGG)
Glycolysis, core module involving three-carbon compounds, conserved biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Metabolic pathways, organism-specific biosystem (from KEGG)
Metabolic pathways, organism-specific biosystem
Metabolic pathways
Metabolism, organism-specific biosystem (from REACTOME)
Metabolism, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Metabolism of carbohydrates, organism-specific biosystem (from REACTOME)
Metabolism of carbohydrates, organism-specific biosystemcomputationally inferred pathway (not manually curated)

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
phosphoglycerate mutase activity	ISS Inferred from Sequence or Structural Similarity more info
phosphoglycerate mutase activity	NAS Non-traceable Author Statement more info

Process	Evidence Code	Pubs
glycolysis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
M band	IDA Inferred from Direct Assay more info	PubMed
Z disc	IDA Inferred from Direct Assay more info	PubMed

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General protein information

Preferred Names: CG1721 gene product from transcript CG1721-RA

Names: CG1721-PA; CG1721-PB; CG1721-PC; Pglym78-PA; Pglym78-PB; Pglym78-PC; phosphoglycerol mutase; phosphoglyceromutase

NP_001034075.1

EC 5.4.2.1

NP_001034076.1

EC 5.4.2.1

NP_524546.2

EC 5.4.2.1

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NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NT_033777.2

Range

24973970..24975623

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_079822.3 → NP_524546.2 phosphoglyceromutase, isoform A [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/TrEMBL

Q9VAN7

Related

FBpp0084753

Conserved Domains (1) summary

cd07067
Location:6 – 90
Blast Score: 281

HP_PGM_like; Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction.
NM_001038987.2 → NP_001034076.1 phosphoglyceromutase, isoform B [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/TrEMBL

Q9VAN7

Related

FBpp0099919

Conserved Domains (1) summary

cd07067
Location:6 – 90
Blast Score: 281

HP_PGM_like; Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction.
NM_001038986.2 → NP_001034075.1 phosphoglyceromutase, isoform C [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/TrEMBL

Q9VAN7

Related

FBpp0099920

Conserved Domains (1) summary

cd07067
Location:6 – 90
Blast Score: 281

HP_PGM_like; Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction.

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Related Sequences

Nucleotide		Protein
Heading	Accession and Version	Protein
genomic	DQ864232.1	ABH06867.1
genomic	DQ864233.1	ABH06868.1
genomic	AE014297.2	ABC66195.1
genomic	DQ864235.1	ABH06870.1
genomic	AE014297.2	ABC66194.1
genomic	HH770067.1	CBX85751.1
genomic	DQ864236.1	ABH06871.1
genomic	DQ864243.1	ABH06878.1
genomic	DQ864228.1	ABH06863.1
genomic	AE014297.2	AAF56866.2
genomic	DQ864231.1	ABH06866.1
genomic	DQ864230.1	ABH06865.1
genomic	DQ864229.1	ABH06864.1
mRNA	AY051464.1	AAK92888.1