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RpL27 Ribosomal protein L27 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43103, updated on 4-Apr-2024

Summary

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Official Symbol
RpL27provided by FlyBase
Official Full Name
Ribosomal protein L27provided by FlyBase
Primary source
FLYBASE:FBgn0039359
Locus tag
Dmel_CG4759
See related
AllianceGenome:FB:FBgn0039359
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG4759; chr3R:21510055..21510241; Dmel\CG4759; L27e; RPL27; RpL27e
Summary
A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Located in cytosolic ribosome. Is expressed in adult head; adult heart; and organism. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 16. Orthologous to human RPL27 (ribosomal protein L27). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
96E9-96E10; 3-88 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25683623..25685051, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21509345..21510773, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Leucine-rich repeat-containing G protein-coupled receptor 3 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma Neighboring gene Cardiolipin synthase Neighboring gene Lipophorin receptor 2 Neighboring gene long non-coding RNA:CR46102

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. New partners in regulation of gene expression: the enhancer of Trithorax and Polycomb Corto interacts with methylated ribosomal protein l12 via its chromodomain. Coléno-Costes A, et al. PLoS Genet, 2012. PMID 23071455, Free PMC Article
  2. Small ribonucleoprotein particle protein SmD3 governs the homeostasis of germline stem cells and the crosstalk between the spliceosome and ribosome signals in Drosophila. Yu J, et al. FASEB J, 2019 Jul. PMID 30921522
  3. DREF is required for cell and organismal growth in Drosophila and functions downstream of the nutrition/TOR pathway. Killip LE, et al. Dev Biol, 2012 Nov 15. PMID 22960233
  4. RpS13 controls the homeostasis of germline stem cell niche through Rho1-mediated signals in the Drosophila testis. Wang M, et al. Cell Prolif, 2020 Oct. PMID 32896929, Free PMC Article
  5. Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB. Scheuermann JC, et al. Nature, 2010 May 13. PMID 20436459, Free PMC Article

See all (59) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytoplasmic translation IC
Inferred by Curator
more info
 PubMed 
involved_in cytoplasmic translation TAS
Traceable Author Statement
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit TAS
Traceable Author Statement
more info
 PubMed 
located_in cytosolic ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosomal protein L27
Names
CG4759-PA
CG4759-PB
CG4759-PC
CG4759-PD
RpL27-PA
RpL27-PB
RpL27-PC
RpL27-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    25683623..25685051 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001276039.1 → NP_001262968.1  ribosomal protein L27, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262968.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VBN5
    Conserved Domains (1) summary
    cl00354
    Location:1 → 135
    KOW; an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)

  2. NM_143160.2 → NP_651417.1  ribosomal protein L27, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651417.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VBN5
    Related
    FBpp0084306
    Conserved Domains (1) summary
    cl00354
    Location:1 → 135
    KOW; an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)

  3. NM_001276038.1 → NP_001262967.1  ribosomal protein L27, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262967.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VBN5
    Conserved Domains (1) summary
    cl00354
    Location:1 → 135
    KOW; an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)

  4. NM_001276037.1 → NP_001262966.1  ribosomal protein L27, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262966.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VBN5
    Conserved Domains (1) summary
    cl00354
    Location:1 → 135
    KOW; an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
4V6W_CZ.1
Q9VBN5 Q9VBN5

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