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    CG4673 [ Drosophila melanogaster ]

    Gene ID: 43091, updated on 5-Feb-2012
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    Summary

    Official Symbol
    CG4673provided by Flybase
    Primary source
    FLYBASE:FBgn0039348
    Locus tag
    Dmel_CG4673
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4673; dNp14; npl4; NPL4
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    Genomic context

    Location :
    96E4-96E6
    Sequence :
    Chromosome: 3R; NT_033777.2 (21436735..21450382, complement)
    See CG4673 in Epigenomics, MapViewer

    Chromosome 3R - NT_033777.2Genomic Context describing neighboring genes Neighboring gene musashi Neighboring gene CG4582 gene product from transcript CG4582-RA Neighboring gene yellow-emperor Neighboring gene CG5079 gene product from transcript CG5079-RA Neighboring gene CG5071 gene product from transcript CG5071-RA Neighboring gene Succinic semialdehyde dehydrogenase Neighboring gene jing interacting gene regulatory 1 Neighboring gene ncRNA

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Genome-wide identification of alternative splice forms down-regulated by nonsense-mediated mRNA decay in Drosophila. Hansen KD, et al. PLoS Genet, 2009 Jun. PMID 19543372.
    2. Wld S requires Nmnat1 enzymatic activity and N16-VCP interactions to suppress Wallerian degeneration. Avery MA, et al. J Cell Biol, 2009 Feb 23. PMID 19237597.
    3. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.
    4. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856.
    5. RNA interference analysis of Legionella in Drosophila cells: exploitation of early secretory apparatus dynamics. Dorer MS, et al. PLoS Pathog, 2006 Apr. PMID 16652170.

    See all (16) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:68004 BioGRID:66107 CG11286    BioGRID  PubMed Two-hybrid 
    BioGRID:68004 BioGRID:61707 CG14744    BioGRID  PubMed Two-hybrid 
    BioGRID:68004 BioGRID:63359 CG15800    BioGRID  PubMed Two-hybrid 
    BioGRID:68004 BioGRID:60196 CG7196    BioGRID  PubMed Two-hybrid 
    BioGRID:68004 BioGRID:60245 CG8455    BioGRID  PubMed Two-hybrid 
    BioGRID:68004 BioGRID:62461 Cdk5    BioGRID  PubMed Two-hybrid 
    BioGRID:68004 BioGRID:58898 CycD    BioGRID  PubMed Two-hybrid 
    BioGRID:68004 BioGRID:68567 CycG    BioGRID  PubMed Two-hybrid 
    BioGRID:68004 BioGRID:65669 CycH    BioGRID  PubMed Two-hybrid 
    BioGRID:68004 BioGRID:72482 CycK    BioGRID  PubMed Two-hybrid 
    BioGRID:68004 BioGRID:59745 Mad    BioGRID  PubMed Two-hybrid 
    BioGRID:68004 BioGRID:61322 RPA2    BioGRID  PubMed Two-hybrid 
    BioGRID:68004 BioGRID:67795 Tsc1    BioGRID  PubMed Two-hybrid 
    BioGRID:68004 BioGRID:64626 Ufd1-like    BioGRID  PubMed Two-hybrid 
    BioGRID:68004 BioGRID:60206 cdc14    BioGRID  PubMed Two-hybrid 
    BioGRID:68004 BioGRID:61832 dap    BioGRID  PubMed Two-hybrid 
    BioGRID:68004 BioGRID:68673 nej    BioGRID  PubMed Two-hybrid 
    BioGRID:68004 BioGRID:61701 ptc    BioGRID  PubMed Two-hybrid 
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    General gene information

    Markers

    Homology

    • Homologs of the CG4673 gene: The CG4673 gene is conserved in human, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, and N.crassa.

    Pathways from BioSystems

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    structural constituent of nuclear pore ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    neurogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		  
    Component Evidence Code Pubs
    nuclear pore ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
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    General protein information

    Preferred Names
    CG4673 gene product from transcript CG4673-RB
    Names
    CG4673
    CG4673-PA
    CG4673-PB
    CG4673-PC
    CG4673-PD
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.2

      Range
      21436735..21450382, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_170231.2 → NP_733110.2  CG4673, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JIX5
      UniProtKB/Swiss-Prot
      Q9VBP9
      Related
      FBpp0084266, FBtr0084892
      Conserved Domains (5) summary
      pfam05020
      Location:112 – 252
      Blast Score: 644
      zf-NPL4; NPL4 family, putative zinc binding region
      cd08061
      Location:220 – 521
      Blast Score: 969
      MPN_NPL4; Mov34/MPN/PAD-1 family: nuclear protein localization-4 (Npl4) domain
      pfam05021
      Location:254 – 565
      Blast Score: 1147
      NPL4; NPL4 family
      cl00155
      Location:5 – 78
      Blast Score: 269
      UBQ; Ubiquitin-like proteins
      cl02656
      Location:599 – 623
      Blast Score: 94
      zf-RanBP; Zn-finger in Ran binding protein and others

    2. NM_001170260.1 → NP_001163731.1  CG4673, isoform D [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JIX5
      UniProtKB/Swiss-Prot
      Q9VBP9
      Related
      FBpp0289954, FBtr0300730
      Conserved Domains (5) summary
      pfam05020
      Location:112 – 252
      Blast Score: 644
      zf-NPL4; NPL4 family, putative zinc binding region
      cd08061
      Location:220 – 521
      Blast Score: 969
      MPN_NPL4; Mov34/MPN/PAD-1 family: nuclear protein localization-4 (Npl4) domain
      pfam05021
      Location:254 – 565
      Blast Score: 1147
      NPL4; NPL4 family
      cl00155
      Location:5 – 78
      Blast Score: 269
      UBQ; Ubiquitin-like proteins
      cl02656
      Location:599 – 623
      Blast Score: 94
      zf-RanBP; Zn-finger in Ran binding protein and others

    3. NM_143150.4 → NP_651407.3  CG4673, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VBP9
      Related
      FBpp0084267, FBtr0084893
      Conserved Domains (5) summary
      pfam05020
      Location:140 – 280
      Blast Score: 645
      zf-NPL4; NPL4 family, putative zinc binding region
      cd08061
      Location:248 – 549
      Blast Score: 967
      MPN_NPL4; Mov34/MPN/PAD-1 family: nuclear protein localization-4 (Npl4) domain
      pfam05021
      Location:282 – 593
      Blast Score: 1147
      NPL4; NPL4 family
      cl00155
      Location:33 – 106
      Blast Score: 267
      UBQ; Ubiquitin-like proteins
      cl02656
      Location:627 – 651
      Blast Score: 93
      zf-RanBP; Zn-finger in Ran binding protein and others

    4. NM_001170259.1 → NP_001163730.1  CG4673, isoform C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JIX6
      Related
      FBpp0289953, FBtr0300729
      Conserved Domains (4) summary
      pfam05020
      Location:41 – 181
      Blast Score: 642
      zf-NPL4; NPL4 family, putative zinc binding region
      cd08061
      Location:149 – 450
      Blast Score: 968
      MPN_NPL4; Mov34/MPN/PAD-1 family: nuclear protein localization-4 (Npl4) domain
      pfam05021
      Location:183 – 494
      Blast Score: 1147
      NPL4; NPL4 family
      cl02656
      Location:528 – 552
      Blast Score: 92
      zf-RanBP; Zn-finger in Ran binding protein and others
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014297.2 AAN14058.2
    genomic AE014297.2 ACZ95025.1
    genomic AE014297.2 AAF56480.3
    mRNA AY058286.2 AAL13515.1
    genomic AE014297.2 ACZ95024.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    Q8IMS6.1 GenPept
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    Additional Links

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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