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    dan distal antenna [ Drosophila melanogaster ]

    Gene ID: 43023, updated on 10-May-2012
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    Summary

    Official Symbol
    danprovided by Flybase
    Official Full Name
    distal antennaprovided by Flybase
    Primary source
    FLYBASE:FBgn0039286
    Locus tag
    Dmel_CG11849
    Gene type
    protein coding
    RNA name
    distal antenna
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11849; Dan; Dmel\CG11849; fer
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    Genomic context

    Location :
    96C3-96C4
    Sequence :
    Chromosome: 3R; NT_033777.2 (21010735..21018528)
    See dan in Epigenomics, MapViewer

    Chromosome 3R - NT_033777.2Genomic Context describing neighboring genes Neighboring gene Band4.1 inhibitor LRP interactor Neighboring gene distal antenna-related Neighboring gene lost boys Neighboring gene CG13653 gene product from transcript CG13653-RA Neighboring gene CG10244 gene product from transcript CG10244-RA Neighboring gene CG13654 gene product from transcript CG13654-RA

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Functional synthetic Antennapedia genes and the dual roles of YPWM motif and linker size in transcriptional activation and repression. Papadopoulos DK, et al. Proc Natl Acad Sci U S A, 2011 Jul 19. PMID 21712439.
    2. The pipsqueak-domain proteins Distal antenna and Distal antenna-related restrict Hunchback neuroblast expression and early-born neuronal identity. Kohwi M, et al. Development, 2011 May. PMID 21429984.
    3. Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50. Yang Y, et al. Mol Biol Cell, 2011 Apr. PMID 21289096.
    4. Drosophila CtBP regulates proliferation and differentiation of eye precursors and complexes with Eyeless, Dachshund, Dan, and Danr during eye and antennal development. Hoang CQ, et al. Dev Dyn, 2010 Sep. PMID 20730908.
    5. Function and specificity of synthetic Hox transcription factors in vivo. Papadopoulos DK, et al. Proc Natl Acad Sci U S A, 2010 Mar 2. PMID 20147626.

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Dan/Danr and Svp act in parallel pathways to limit Hb expression and allow neuroblasts to transition from making early-born neurons to late-born neurons at the proper time.
      Title: The pipsqueak-domain proteins Distal antenna and Distal antenna-related restrict Hunchback neuroblast expression and early-born neuronal identity.
    2. Dan and Danr have roles in Drosophila eye development
      Title: distal antenna and distal antenna-related function in the retinal determination network during eye development in Drosophila.
    3. fernandez and hernandez genes are required in the nervous system during the embryonic development
      Title: Expression analysis of the Drosophila pipsqueak family members fernández/distal antenna and hernández/distal antenna related.
    4. results show that the hernandez and fernandez genes are required for antennal and eye development and are also able to specify eye or antenna ectopically
      Title: The hernandez and fernandez genes of Drosophila specify eye and antenna.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:67943 BioGRID:58854 CG8128    BioGRID  PubMed Two-hybrid 
    BioGRID:67943 BioGRID:62567 Cdk4    BioGRID  PubMed Two-hybrid 
    BioGRID:67943 BioGRID:59745 Mad    BioGRID  PubMed Two-hybrid 
    BioGRID:67943 BioGRID:60215 SmE    BioGRID  PubMed Two-hybrid 
    BioGRID:67943 BioGRID:65883 rev7    BioGRID  PubMed Two-hybrid 
    BioGRID:67943 BioGRID:58031 rux    BioGRID  PubMed Two-hybrid 
    BioGRID:67943 BioGRID:62080 skpB    BioGRID  PubMed Two-hybrid 
    BioGRID:67943 BioGRID:67033 ss    BioGRID  PubMed Phenotypic Suppression 
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    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    DNA binding NAS
    Non-traceable Author Statement
    more info
    		  
    protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    sequence-specific DNA binding transcription factor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    compound eye development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    regulation of transcription, DNA-dependent IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    segment specification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    CG11849 gene product from transcript CG11849-RA
    Names
    CG11849-PA
    dan-PA
    distal antenna
    fernandez
    tintin
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.2

      Range
      21010735..21018528
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143089.3 → NP_651346.1  distal antenna [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VBW6
      Related
      FBpp0084178, FBtr0084803
      Conserved Domains (1) summary
      pfam04218
      Location:10 – 62
      Blast Score: 211
      CENP-B_N; CENP-B N-terminal DNA-binding domain
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014297.2 AAF56411.2
    mRNA AY051924.1 AAK93348.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VBW6.2 GenPept
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    Additional Links

    Gene LinkOut

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