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SOCS5 suppressor of cytokine signaling 5 [ Gallus gallus (chicken) ]

Gene ID: 428570, updated on 11-Apr-2024

Summary

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Symbol
SOCS5provided by CGNC
Full Name
suppressor of cytokine signaling 5provided by CGNC
Primary source
CGNC:7613
See related
Ensembl:ENSGALG00010018511
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
3
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (26502463..26533183)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (26385049..26459171)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene CXXC repeat containing interactor of PDZ3 domain Neighboring gene uncharacterized LOC101751536 Neighboring gene uncharacterized LOC121110336 Neighboring gene uncharacterized LOC112532217 Neighboring gene multiple coagulation factor deficiency 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. MicroRNA gga-miR-130b Suppresses Infectious Bursal Disease Virus Replication via Targeting of the Viral Genome and Cellular Suppressors of Cytokine Signaling 5. Fu M, et al. J Virol, 2018 Jan 1. PMID 29046449, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in epidermal growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
suppressor of cytokine signaling 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127314.1 → NP_001120786.1  suppressor of cytokine signaling 5

    See identical proteins and their annotated locations for NP_001120786.1

    Status: PROVISIONAL

    Source sequence(s)
    EF544592
    UniProtKB/TrEMBL
    B2WUP1
    Related
    ENSGALP00010026704.1, ENSGALT00010044782.1
    Conserved Domains (3) summary
    cd03739
    Location:479 → 535
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 195
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    26502463..26533183
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040697277.2 → XP_040553211.1  suppressor of cytokine signaling 5 isoform X1

    UniProtKB/TrEMBL
    B2WUP1
    Related
    ENSGALP00010026714.1, ENSGALT00010044792.1
    Conserved Domains (3) summary
    cd03739
    Location:479 → 535
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 195
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain

  2. XM_040697278.2 → XP_040553212.1  suppressor of cytokine signaling 5 isoform X1

    UniProtKB/TrEMBL
    B2WUP1
    Related
    ENSGALP00010026710.1, ENSGALT00010044788.1
    Conserved Domains (3) summary
    cd03739
    Location:479 → 535
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 195
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    26385049..26459171
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046914322.1 → XP_046770278.1  suppressor of cytokine signaling 5 isoform X1

    UniProtKB/TrEMBL
    B2WUP1

  2. XM_046914319.1 → XP_046770275.1  suppressor of cytokine signaling 5 isoform X1

    UniProtKB/TrEMBL
    B2WUP1

  3. XM_046914320.1 → XP_046770276.1  suppressor of cytokine signaling 5 isoform X1

    UniProtKB/TrEMBL
    B2WUP1

  4. XM_046914318.1 → XP_046770274.1  suppressor of cytokine signaling 5 isoform X1

    UniProtKB/TrEMBL
    B2WUP1

  5. XM_046914321.1 → XP_046770277.1  suppressor of cytokine signaling 5 isoform X1

    UniProtKB/TrEMBL
    B2WUP1
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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