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    cdc2c [ Drosophila melanogaster ]

    Gene ID: 42453, updated on 10-May-2012

    Summary

    Official Symbol
    cdc2cprovided by Flybase
    Primary source
    FLYBASE:FBgn0004107
    Locus tag
    Dmel_CG10498
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Cdc2c; CDC2c; CDC2C; cdk2; Cdk2; CDK2; CDK2/CDC2c; CG10498; Dcdc2c; dCdk2; DmCdc2; Dmcdc2c; DmCdk2; Dmel\CG10498; S(Sev-CycE)3A

    Genomic context

    Location :
    92F10-92F10
    Sequence :
    Chromosome: 3R; NT_033777.2 (16561342..16563260)
    See cdc2c in Epigenomics, MapViewer

    Chromosome 3R - NT_033777.2Genomic Context describing neighboring genes Neighboring gene CG31205 gene product from transcript CG31205-RB Neighboring gene pseudo Neighboring gene mir-995 stem loop Neighboring gene CG17267 gene product from transcript CG17267-RA Neighboring gene CG42322 gene product from transcript CG42322-RI Neighboring gene CG31199 gene product from transcript CG31199-RA Neighboring gene CG31200 gene product from transcript CG31200-RA

    Bibliography

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    NP_732544.1 NP_648308.1 CG3689    BIND  PubMed cdc2c (Cdk2) interacts with CG3689 (Cdi12). 
    NP_732544.1 NP_476947.1 Cks30A    BIND  PubMed cdc2c (Cdk2) interacts with Cks (Cdi2). 
    NP_732544.1 NP_523355.1 CycD    BIND  PubMed cdc2c (Cdk2) interacts with CycD (Cdi3). 
    NP_732544.1 CycJ    BIND  PubMed cdc2c (Cdk2) interacts with an unspecified isoform of CycJ (Cdi5). 
    BioGRID:67428 BioGRID:61134 CG10600    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:67857 CG13625    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:64811 CG14119    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:67185 CG14317    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:533580 CG14425    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:59406 CG14619    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:60644 CG14937    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:59148 CG15043    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:63098 CG15676    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:72486 CG17508    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:61892 CG18011    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:78265 CG40282    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:60452 CG5708    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:60446 CG5731    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:62268 CG6191    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:66406 CG6293    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:62567 Cdk4    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:66209 Cks85A    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:66871 CycC    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:60939 CycE    BioGRID  PubMed Affinity Capture-MS; Phenotypic Enhancement; Phenotypic Suppression 
    BioGRID:67428 BioGRID:68567 CycG    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:65669 CycH    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:63921 CycJ    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:72482 CycK    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:66030 Dfd    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:61444 EcR    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:59683 Hrs    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:59479 MED15    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:63381 PHDP    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:57689 Pgam5    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:68299 Pkc98E    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:72126 Pp1-87B    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:67407 Stat92E    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:67428 BioGRID:59992 Vm26Ab    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:61832 dap    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:61353 dimm    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:64769 eyg    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:64513 fry    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:61396 gus    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:65883 rev7    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:78013 rl    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:66236 skap    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:68433 spn-A    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:62194 sug    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:68659 toy    BioGRID  PubMed Two-hybrid 
    BioGRID:67428 BioGRID:68196 wdb    BioGRID  PubMed Two-hybrid 

    General gene information

    Pathways from BioSystems

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    cyclin-dependent protein kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    cyclin-dependent protein kinase activity NAS
    Non-traceable Author Statement
    more info
     
    protein serine/threonine kinase activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    G1/S transition of mitotic cell cycle ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    G2/M transition of mitotic cell cycle ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    JAK-STAT cascade IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    cellular process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    protein phosphorylation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    regulation of cell cycle NAS
    Non-traceable Author Statement
    more info
     
    Component Evidence Code Pubs
    microtubule associated complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    CG10498 gene product from transcript CG10498-RC
    Names
    CG10498-PA
    CG10498-PB
    CG10498-PC
    cdc2c
    cdc2c-PA
    cdc2c-PB
    cdc2c-PC
    cyclin E-CDK2
    cyclin-dependent kinase 2
    NP_001163666.1
    NP_524420.1
    NP_732544.1

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.2

      Range
      16561342..16563260
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001170195.1NP_001163666.1  cdc2c, isoform C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JIR3
      UniProtKB/Swiss-Prot
      P23573
      Related
      FBpp0289675, FBtr0300447
      Conserved Domains (2) summary
      cd07835
      Location:8287
      Blast Score: 1364
      STKc_CDK1_like; Catalytic domain of Cyclin-Dependent protein Kinase 1-like Serine/Threonine Kinases
      PLN00009
      Location:5293
      Blast Score: 1037
      PLN00009; cyclin-dependent kinase A; Provisional
    2. NM_079696.5NP_524420.1  cdc2c, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JIR3
      UniProtKB/Swiss-Prot
      P23573
      Related
      FBpp0083330, FBtr0083922
      Conserved Domains (2) summary
      cd07835
      Location:8287
      Blast Score: 1364
      STKc_CDK1_like; Catalytic domain of Cyclin-Dependent protein Kinase 1-like Serine/Threonine Kinases
      PLN00009
      Location:5293
      Blast Score: 1037
      PLN00009; cyclin-dependent kinase A; Provisional
    3. NM_169916.2NP_732544.1  cdc2c, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JIR3
      UniProtKB/Swiss-Prot
      P23573
      Related
      FBpp0083329, FBtr0083921
      Conserved Domains (2) summary
      cd07835
      Location:8287
      Blast Score: 1364
      STKc_CDK1_like; Catalytic domain of Cyclin-Dependent protein Kinase 1-like Serine/Threonine Kinases
      PLN00009
      Location:5293
      Blast Score: 1037
      PLN00009; cyclin-dependent kinase A; Provisional

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014297.2 AAF55799.1
    genomic AE014297.2 AAN14363.1
    genomic AE014297.2 ACZ94962.1
    mRNA AY051671.1 AAK93095.1
    mRNA X57486.1 CAA40724.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    P23573.1 GenPept

      Supplemental Content