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CG6231 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42339, updated on 4-Apr-2024

Summary

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Official Symbol
CG6231provided by FlyBase
Primary source
FLYBASE:FBgn0038720
Locus tag
Dmel_CG6231
See related
AllianceGenome:FB:FBgn0038720
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG6231
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be integral component of membrane. Is expressed in adult head. Orthologous to several human genes including SLC22A10 (solute carrier family 22 member 10); SLC22A11 (solute carrier family 22 member 11); and SLC22A15 (solute carrier family 22 member 15). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
92A10-92A11; 3-66 cM
Exon count:
12
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (19616024..19632718, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (15441746..15458440, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene mir-9373 stem loop Neighboring gene subdued Neighboring gene uncharacterized protein Neighboring gene Vacuolar H[+] ATPase 13kD subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II. Chen FX, et al. Cell, 2015 Aug 27. PMID 26279188, Free PMC Article
  2. Genetic and metabolomic architecture of variation in diet restriction-mediated lifespan extension in Drosophila. Jin K, et al. PLoS Genet, 2020 Jul. PMID 32644988, Free PMC Article
  3. Highly rearranged chromosomes reveal uncoupling between genome topology and gene expression. Ghavi-Helm Y, et al. Nat Genet, 2019 Aug. PMID 31308546, Free PMC Article
  4. Identification of the Telomere elongation Mutation in Drosophila. Reddy HM, et al. Cells, 2022 Nov 3. PMID 36359878, Free PMC Article
  5. Revisiting the protein-coding gene catalog of Drosophila melanogaster using 12 fly genomes. Lin MF, et al. Genome Res, 2007 Dec. PMID 17989253, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG6231-PA
CG6231-PB
CG6231-PC
CG6231-PD
CG6231-PE
CG6231-PF
organic cation transporter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    19616024..19632718 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_169865.2 → NP_732436.1  uncharacterized protein Dmel_CG6231, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732436.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SX51, Q9VDV5
    Related
    FBpp0083217
    Conserved Domains (2) summary
    cd06174
    Location:125 → 499
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:11 → 509
    2A0119; cation transport protein

  2. NM_169866.3 → NP_732437.1  uncharacterized protein Dmel_CG6231, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732437.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SX51, Q9VDV5
    Related
    FBpp0083218
    Conserved Domains (2) summary
    cd06174
    Location:125 → 499
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:11 → 509
    2A0119; cation transport protein

  3. NM_001275805.1 → NP_001262734.1  uncharacterized protein Dmel_CG6231, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262734.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SX51, Q9VDV5
    Conserved Domains (2) summary
    cd06174
    Location:125 → 499
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:11 → 509
    2A0119; cation transport protein

  4. NM_169864.2 → NP_732435.1  uncharacterized protein Dmel_CG6231, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732435.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SX51, Q9VDV5
    Related
    FBpp0083219
    Conserved Domains (2) summary
    cd06174
    Location:125 → 499
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:11 → 509
    2A0119; cation transport protein

  5. NM_001275806.1 → NP_001262735.1  uncharacterized protein Dmel_CG6231, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262735.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SX51, Q9VDV5
    Conserved Domains (2) summary
    cd06174
    Location:125 → 499
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:11 → 509
    2A0119; cation transport protein

  6. NM_142562.3 → NP_650819.1  uncharacterized protein Dmel_CG6231, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650819.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SX51, Q9VDV5
    Related
    FBpp0083220
    Conserved Domains (2) summary
    cd06174
    Location:125 → 499
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:11 → 509
    2A0119; cation transport protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SX51 Q8SX51
Q9VDV5 Q9VDV5

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