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    Dlc90F Dynein light chain 90F [ Drosophila melanogaster ]

    Gene ID: 42199, updated on 10-May-2012
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    Summary

    Official Symbol
    Dlc90Fprovided by Flybase
    Official Full Name
    Dynein light chain 90Fprovided by Flybase
    Primary source
    FLYBASE:FBgn0024432
    Locus tag
    Dmel_CG12363
    Gene type
    protein coding
    RNA name
    dynein light chain 90F
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    bs35g12.y1; CG12363; dlc90F; Dmel\CG12363; dtctex-1; l(3)04091; tctex; Tctex; tctex-1; Tctex-1; TcTex-1
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    Genomic context

    Location :
    91A2-91A2
    Sequence :
    Chromosome: 3R; NT_033777.2 (14124927..14125764)
    See Dlc90F in Epigenomics, MapViewer

    Chromosome 3R - NT_033777.2Genomic Context describing neighboring genes Neighboring gene CG8064 gene product from transcript CG8064-RA Neighboring gene CG7131 gene product from transcript CG7131-RA Neighboring gene lethal (3) 05822 Neighboring gene CG18600 gene product from transcript CG18600-RA Neighboring gene CG7126 gene product from transcript CG7126-RA

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573.
    2. The Drosophila SUN protein Spag4 cooperates with the coiled-coil protein Yuri Gagarin to maintain association of the basal body and spermatid nucleus. Kracklauer MP, et al. J Cell Sci, 2010 Aug 15. PMID 20647369.
    3. Genome-wide analysis of low-dose irradiated male Drosophila melanogaster with extended longevity. Seong KM, et al. Biogerontology, 2011 Apr. PMID 20617381.
    4. Dynein light chain 1 is required for autophagy, protein clearance, and cell death in Drosophila. Batlevi Y, et al. Proc Natl Acad Sci U S A, 2010 Jan 12. PMID 20080745.
    5. Dynein-dynactin complex is essential for dendritic restriction of TM1-containing Drosophila Dscam. Yang JS, et al. PLoS One, 2008. PMID 18946501.

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Dynein light chain 1 is required for protein clearance by autophagy that is associated with autophagic cell death and neurodegeneration.
      Title: Dynein light chain 1 is required for autophagy, protein clearance, and cell death in Drosophila.
    2. Interactions of cytoplasmic dynein light chains Tctex-1 and LC8 with the intermediate chain IC74
      Title: Interactions of cytoplasmic dynein light chains Tctex-1 and LC8 with the intermediate chain IC74.
    3. Dlc90F is required for the localization of cytoplasmic dynein and is not essential for early development or in the adult organism.
      Title: The Drosophila tctex-1 light chain is dispensable for essential cytoplasmic dynein functions but is required during spermatid differentiation.
    4. x-ray crystallographic analysis of dynein light chain TcTex-1 structure
      Title: Crystal structure of dynein light chain TcTex-1.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:67217 BioGRID:66029 Ama    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:67217 BioGRID:66976 Arpc3A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:67217 BioGRID:59928 Bsg25D    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:66048 CG10098    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:64858 CG10133    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:67217 BioGRID:58710 CG10990    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:65192 CG13022    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:64415 CG13312    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:61619 CG14763    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:67217 BioGRID:63435 CG16786    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:68490 CG2267    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:73196 CG30497    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:67235 CG31122    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:67724 CG31145    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:76716 CG32581    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:928289 CG42232    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:67217 BioGRID:66379 CG5359    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:59571 CG5565    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:67800 CG6178    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:67193 CG7208    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:58880 CG8974    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:58944 Fur2    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:64472 Hsp23    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:64468 Hsp67Bc    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:59950 Lam    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:67217 BioGRID:66387 Npc2d    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:61062 Oli    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:62771 Ote    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:67574 PSR    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:67217 BioGRID:59240 Pfrx    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:61322 RPA2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:67217 BioGRID:77420 Tap42    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:67217 BioGRID:60561 UbcD2    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:68580 awd    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:62866 ena    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:60293 grk    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:62421 igl    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:67217 BioGRID:63731 metl    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:61230 msb1l    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:69987 rap    BioGRID  PubMed Two-hybrid 
    BioGRID:67217 BioGRID:58984 spheroide    BioGRID  PubMed Affinity Capture-MS 
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    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    ATPase activity, coupled ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    dynein intermediate chain binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    microtubule-based movement ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    mitosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    spermatid development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    dynein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    microtubule associated complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    microtubule associated complex NAS
    Non-traceable Author Statement
    more info
    		  
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    General protein information

    Preferred Names
    CG12363 gene product from transcript CG12363-RA
    Names
    CG12363-PA
    Dlc90F-PA
    dynein light chain 90F
    dynein light chain; tctex-1
    NP_477356.1
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.2

      Range
      14124927..14125764
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058008.3 → NP_477356.1  dynein light chain 90F [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94524
      Related
      FBpp0082996, FBtr0083575
      Conserved Domains (1) summary
      pfam03645
      Location:12 – 111
      Blast Score: 350
      Tctex-1; Tctex-1 family
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014297.2 AAF55532.1
    genomic AF123058.1 AAD30033.1
    mRNA Y08968.1 CAA70165.1
    mRNA AY069608.1 AAL39753.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    3FM7_A.1 GenPept
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    Additional Links

    Gene LinkOut

      Supplemental Content

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