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CG7523 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42125, updated on 4-Apr-2024

Summary

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Official Symbol
CG7523provided by FlyBase
Primary source
FLYBASE:FBgn0038533
Locus tag
Dmel_CG7523
See related
AllianceGenome:FB:FBgn0038533
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG7523
Summary
Predicted to be active in late endosome and lysosomal membrane. Is expressed in adult head and adult heart. Orthologous to human TMEM192 (transmembrane protein 192). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
90C1-90C1; 3-61 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (17669144..17670895, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (13494866..13496617, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene transfer RNA:Alanine-AGC 2-10 Neighboring gene uncharacterized protein Neighboring gene Monopolar spindle 1 Neighboring gene aluminum tubes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The meiotic defects of mutants in the Drosophila mps1 gene reveal a critical role of Mps1 in the segregation of achiasmate homologs. Gilliland WD, et al. Curr Biol, 2005 Apr 12. PMID 15823541
  2. The mitotic arrest in response to hypoxia and of polar bodies during early embryogenesis requires Drosophila Mps1. Fischer MG, et al. Curr Biol, 2004 Nov 23. PMID 15556864
  3. An amino acid polymorphism in the couch potato gene forms the basis for climatic adaptation in Drosophila melanogaster. Schmidt PS, et al. Proc Natl Acad Sci U S A, 2008 Oct 21. PMID 18852464, Free PMC Article
  4. Genome-wide examination of the transcriptional response to ecdysteroids 20-hydroxyecdysone and ponasterone A in Drosophila melanogaster. Gonsalves SE, et al. BMC Genomics, 2011 Sep 29. PMID 21958154, Free PMC Article
  5. Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Hollien J, et al. Science, 2006 Jul 7. PMID 16825573

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Component Evidence Code Pubs
is_active_in late endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in lysosomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7523-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    17669144..17670895 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142386.4 → NP_650643.2  uncharacterized protein Dmel_CG7523 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650643.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6NL61, Q9VEH2
    Related
    FBpp0082923
    Conserved Domains (1) summary
    pfam14802
    Location:23 → 247
    TMEM192; TMEM192 family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q95SY0 Q95SY0
Q9VEH2 Q9VEH2

Gene LinkOut

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