My NCBISign In

Display Settings:

Format

Send to:

Choose Destination

    CG5840 [ Drosophila melanogaster ]

    Gene ID: 42106, updated on 10-May-2012
    Help top of page

    Summary

    Official Symbol
    CG5840provided by Flybase
    Primary source
    FLYBASE:FBgn0038516
    Locus tag
    Dmel_CG5840
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CT18319; Dmel\CG5840
    Help top of page

    Genomic context

    Location :
    90B3-90B3
    Sequence :
    Chromosome: 3R; NT_033777.2 (13361409..13362858)
    See CG5840 in Epigenomics, MapViewer

    Chromosome 3R - NT_033777.2Genomic Context describing neighboring genes Neighboring gene Down syndrome cell adhesion molecule 3 Neighboring gene CG5823 gene product from transcript CG5823-RA Neighboring gene lethal (3) 07882 Neighboring gene Splicing factor 1 Neighboring gene Peroxiredoxin 3

    Help top of page

    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
    Helptop of page

    Bibliography

    Related articles in PubMed

    1. Mating alters gene expression patterns in Drosophila melanogaster male heads. Ellis LL, et al. BMC Genomics, 2010 Oct 11. PMID 20937114.
    2. Nutrition controls mitochondrial biogenesis in the Drosophila adipose tissue through Delg and cyclin D/Cdk4. Baltzer C, et al. PLoS One, 2009 Sep 9. PMID 19742324.
    3. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.
    4. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856.
    5. Combined evidence annotation of transposable elements in genome sequences. Quesneville H, et al. PLoS Comput Biol, 2005 Jul. PMID 16110336.

    See all (12) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
    Help top of page

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:67141 BioGRID:68563 CG1635    BioGRID  PubMed Two-hybrid 
    BioGRID:67141 BioGRID:67141 CG5840    BioGRID  PubMed Two-hybrid 
    BioGRID:67141 BioGRID:67172 CG7379    BioGRID  PubMed Two-hybrid 
    BioGRID:67141 BioGRID:72482 CycK    BioGRID  PubMed Two-hybrid 
    BioGRID:67141 BioGRID:65820 opa    BioGRID  PubMed Two-hybrid 
    Help top of page

    General gene information

    Homology

    • Homologs of the CG5840 gene: The CG5840 gene is conserved in human, chimpanzee, , dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, S.cerevisiae, K.lactis, , S.pombe, , N.crassa, A.thaliana, rice, and P.falciparum.

    Pathways from BioSystems

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  
    pyrroline-5-carboxylate reductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
    		  
    proline biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Help top of page

    General protein information

    Preferred Names
    CG5840 gene product from transcript CG5840-RB
    Names
    CG5840
    CG5840-PA
    CG5840-PB
    Pyrroline-5-carboxylate reductase
    NP_650632.1
    NP_732243.1
    Help top of page

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.2

      Range
      13361409..13362858
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_169762.1 → NP_732243.1  CG5840, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IN96
      Related
      FBpp0082896, FBtr0083455
      Conserved Domains (1) summary
      cl09931
      Location:2 – 171
      Blast Score: 524
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    2. NM_142375.2 → NP_650632.1  CG5840, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VEJ3
      Related
      FBpp0082895, FBtr0083454
      Conserved Domains (2) summary
      PRK11880
      Location:6 – 271
      Blast Score: 595
      PRK11880; pyrroline-5-carboxylate reductase; Reviewed
      cl09931
      Location:6 – 270
      Blast Score: 605
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Help top of page

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014297.2 AAN13746.1
    mRNA AY071558.1 AAL49180.1
    mRNA BT010232.1 AAQ23550.1
    genomic HC750541.1 CBM38432.1
    genomic AE014297.2 AAF55428.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IN96.1 GenPept
    Help top of page

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

      Supplemental Content