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KPNA6 karyopherin subunit alpha 6 [ Gallus gallus (chicken) ]

Gene ID: 419656, updated on 3-Apr-2024

Summary

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Official Symbol
KPNA6provided by CGNC
Official Full Name
karyopherin subunit alpha 6provided by CGNC
Primary source
CGNC:51052
See related
Ensembl:ENSGALG00010017539
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 23
Exon count:
17
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 23 NC_052554.1 (5538331..5554406, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 23 NC_052595.1 (5301717..5317792, complement)

Chromosome 23 - NC_052554.1Genomic Context describing neighboring genes Neighboring gene IQ motif containing C Neighboring gene coiled-coil domain containing 28B Neighboring gene taxilin alpha Neighboring gene family with sequence similarity 229 member A Neighboring gene testis specific serine kinase 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A comprehensive collection of chicken cDNAs. Boardman PE, et al. Curr Biol, 2002 Nov 19. PMID 12445392
  2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nuclear import signal receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear localization sequence binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in NLS-bearing protein import into nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
importin subunit alpha-7
Names
karyopherin alpha 6 (importin alpha 7)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012841.3 → NP_001012859.2  importin subunit alpha-7

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000339
    UniProtKB/TrEMBL
    A0A8V0Z204, F7B5S0
    Related
    ENSGALP00010024942.1, ENSGALT00010042452.1
    Conserved Domains (3) summary
    COG5064
    Location:36 → 525
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00044
    Location:87 → 115
    HEAT; HEAT repeat [structural motif]
    sd00043
    Location:255 → 280
    ARM; armadillo repeat [structural motif]

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052554.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    5538331..5554406 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046903558.1 → XP_046759514.1  importin subunit alpha-7 isoform X2

    UniProtKB/TrEMBL
    Q5ZJZ0
    Related
    ENSGALP00010024921.1, ENSGALT00010042431.1

  2. XM_046903560.1 → XP_046759516.1  importin subunit alpha-7 isoform X2

    UniProtKB/TrEMBL
    Q5ZJZ0

  3. XM_046903561.1 → XP_046759517.1  importin subunit alpha-7 isoform X2

    UniProtKB/TrEMBL
    Q5ZJZ0

  4. XM_015297668.4 → XP_015153154.1  importin subunit alpha-7 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YV14, A0A8V0Z204
    Related
    ENSGALP00010024903.1, ENSGALT00010042411.1
    Conserved Domains (6) summary
    COG5064
    Location:50 → 539
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    cd00020
    Location:266 → 380
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    pfam01749
    Location:23 → 117
    IBB; Importin beta binding domain
    pfam16186
    Location:479 → 522
    Arm_3; Atypical Arm repeat
    sd00044
    Location:101 → 129
    HEAT; HEAT repeat [structural motif]
    sd00043
    Location:269 → 294
    ARM; armadillo repeat [structural motif]

  5. XM_046903559.1 → XP_046759515.1  importin subunit alpha-7 isoform X2

    UniProtKB/TrEMBL
    Q5ZJZ0

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052595.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    5301717..5317792 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046931977.1 → XP_046787933.1  importin subunit alpha-7 isoform X2

    UniProtKB/TrEMBL
    Q5ZJZ0

  2. XM_046931979.1 → XP_046787935.1  importin subunit alpha-7 isoform X2

    UniProtKB/TrEMBL
    Q5ZJZ0

  3. XM_046931980.1 → XP_046787936.1  importin subunit alpha-7 isoform X2

    UniProtKB/TrEMBL
    Q5ZJZ0

  4. XM_046931976.1 → XP_046787932.1  importin subunit alpha-7 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YV14

  5. XM_046931978.1 → XP_046787934.1  importin subunit alpha-7 isoform X2

    UniProtKB/TrEMBL
    Q5ZJZ0
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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