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    folA dihydrofolate reductase [ Haloquadratum walsbyi DSM 16790 ]

    Gene ID: 4193990, updated on 18-May-2013
    Gene symbol
    folA
    Gene description
    dihydrofolate reductase
    Locus tag
    HQ1842A
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Haloquadratum walsbyi DSM 16790 (strain: strain: DSM 16790 = HBSQ001)
    Lineage
    Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae; Haloquadratum
    Sequence :
    NC_008212.1 (1028119..1028601)

    NC_008212.1Genomic Context describing neighboring genes Neighboring gene short chain dehydrogenase/ reductase Neighboring gene major facilitator superfamily transporter Neighboring gene methionine sulfoxide reductase A Neighboring gene gamma-glutamyl phosphate reductase

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. Genome information management and integrated data analysis with HaloLex. Pfeiffer F, et al. Arch Microbiol, 2008 Sep. PMID 18592220.
    2. The genome of the square archaeon Haloquadratum walsbyi : life at the limits of water activity. Bolhuis H, et al. BMC Genomics, 2006 Jul 4. PMID 16820047.

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
    Names
    dihydrofolate reductase
    YP_657608.1

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_008212.1

      Range
      1028119..1028601
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_657608.1 dihydrofolate reductase [Haloquadratum walsbyi DSM 16790]

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q18J41
      Conserved Domains (2) summary
      COG0262
      Location:6 – 151
      Blast Score: 287
      FolA; Dihydrofolate reductase [Coenzyme metabolism]
      cd00209
      Location:3 – 146
      Blast Score: 384
      DHFR; Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5, ...
    Nucleotide Protein
    Heading Accession and Version
    genomic AM180088.1 CAJ51970.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

      Supplemental Content

      Table of contents

      Related information

      • BioProjects
        BioProjects related to a gene
      • BioSystems
        BioSystems
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • Full text in PMC
        PMC links
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • Genome
        Genome records having the gene annotated on corresponding genomic reference sequence.
      • Nucleotide
        Link to related Nucleotide entry
      • Protein
        Link to related protein entry
      • Protein Clusters
        Related Protein Clusters
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • Taxonomy
        Link to related taxonomy entry

      Links to other resources

      General information

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