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    CG14869 [ Drosophila melanogaster ]

    Gene ID: 41887, updated on 10-May-2012
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    Summary

    Official Symbol
    CG14869provided by Flybase
    Primary source
    FLYBASE:FBgn0038341
    Locus tag
    Dmel_CG14869
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG6107; CT19033; Dmel\CG14869
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    Genomic context

    Location :
    88F5-88F6
    Sequence :
    Chromosome: 3R; NT_033777.2 (11267965..11301915, complement)
    See CG14869 in Epigenomics, MapViewer

    Chromosome 3R - NT_033777.2Genomic Context describing neighboring genes Neighboring gene CG6118 gene product from transcript CG6118-RC Neighboring gene Actin 88F Neighboring gene CG14870 gene product from transcript CG14870-RA Neighboring gene Rhodopsin 6

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. Blanco E, et al. BMC Dev Biol, 2010 Sep 2. PMID 20813047.
    2. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.
    3. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856.
    4. Combined evidence annotation of transposable elements in genome sequences. Quesneville H, et al. PLoS Comput Biol, 2005 Jul. PMID 16110336.
    5. Functional evolution of ADAMTS genes: evidence from analyses of phylogeny and gene organization. Nicholson AC, et al. BMC Evol Biol, 2005 Feb 4. PMID 15693998.

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:66948 BioGRID:61128 CG15167    BioGRID  PubMed Two-hybrid 
    BioGRID:66948 BioGRID:59864 CG15631    BioGRID  PubMed Two-hybrid 
    BioGRID:66948 BioGRID:72813 CG18745    BioGRID  PubMed Two-hybrid 
    BioGRID:66948 BioGRID:60343 CG31708    BioGRID  PubMed Two-hybrid 
    BioGRID:66948 BioGRID:72631 CG32354    BioGRID  PubMed Two-hybrid 
    BioGRID:66948 BioGRID:57825 CG3939    BioGRID  PubMed Two-hybrid 
    BioGRID:66948 BioGRID:58929 CG9911    BioGRID  PubMed Two-hybrid 
    BioGRID:66948 BioGRID:62074 Drep-1    BioGRID  PubMed Two-hybrid 
    BioGRID:66948 BioGRID:61484 Epac    BioGRID  PubMed Two-hybrid 
    BioGRID:66948 BioGRID:58808 PPYR1    BioGRID  PubMed Two-hybrid 
    BioGRID:66948 BioGRID:57901 Usf    BioGRID  PubMed Two-hybrid 
    BioGRID:66948 BioGRID:58863 l(1)G0136    BioGRID  PubMed Two-hybrid 
    BioGRID:66948 BioGRID:58140 unc-119    BioGRID  PubMed Two-hybrid 
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    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    metalloendopeptidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    proteinaceous extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Preferred Names
    CG14869 gene product from transcript CG14869-RB
    Names
    CG14869
    CG14869-PA
    CG14869-PB
    NP_732036.2
    NP_996218.1
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.2

      Range
      11267965..11301915, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206496.1 → NP_996218.1  CG14869, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SXB0
      Related
      FBpp0082614, FBtr0083160
      Conserved Domains (6) summary
      cd04273
      Location:455 – 655
      Blast Score: 540
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam08685
      Location:1492 – 1688
      Blast Score: 709
      GON; GON domain
      pfam12115
      Location:696 – 745
      Blast Score: 88
      Salp15; Salivary protein of 15kDa inhibits CD4+ T cell activation
      cl15278
      Location:754 – 806
      Blast Score: 164
      TSP_1; Thrombospondin type 1 domain
      pfam01562
      Location:295 – 400
      Blast Score: 216
      Pep_M12B_propep; Reprolysin family propeptide
      pfam05986
      Location:937 – 1042
      Blast Score: 163
      ADAM_spacer1; ADAM-TS Spacer 1

    2. NM_169659.2 → NP_732036.2  CG14869, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KSH7
      Related
      FBpp0082613, FBtr0083159
      Conserved Domains (6) summary
      cd04273
      Location:304 – 504
      Blast Score: 538
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam08685
      Location:1341 – 1537
      Blast Score: 707
      GON; GON domain
      pfam12115
      Location:545 – 594
      Blast Score: 87
      Salp15; Salivary protein of 15kDa inhibits CD4+ T cell activation
      cl15278
      Location:603 – 655
      Blast Score: 163
      TSP_1; Thrombospondin type 1 domain
      pfam01562
      Location:144 – 249
      Blast Score: 216
      Pep_M12B_propep; Reprolysin family propeptide
      pfam05986
      Location:786 – 891
      Blast Score: 163
      ADAM_spacer1; ADAM-TS Spacer 1
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014297.2 AAS65157.1
    mRNA AY094716.1 AAM11069.1
    genomic AE014297.2 AAF55199.3
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SXB0.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

      Supplemental Content