NCK2 NCK adaptor protein 2 [Gallus gallus] - Gene

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Summary

Symbol: NCK2provided by CGNC
Full Name: NCK adaptor protein 2provided by CGNC
Primary source: CGNC:50836
Locus tag: RCJMB04_13d16
See related: Ensembl:ENSGALG00000016799
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus
Annotation information: Annotation category: partial on reference assembly

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Genomic context

Location :: chromosome: 1

Sequence :: Chromosome: 1; NC_006088.3 (134633920..134715558)

See NCK2 in MapViewer

Chromosome 1 - NC_006088.3 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

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General gene information

Pathways from BioSystems

EGFR1 Signaling Pathway, organism-specific biosystem (from WikiPathways)
EGFR1 Signaling Pathway, organism-specific biosystemThe androgen receptor is a member of the nuclear receptor family of ligand activated transcription factors. These receptors bind to steroid hormones, thyroid hormone, retinoids and vitamin D among ot...
ErbB signaling pathway, organism-specific biosystem (from KEGG)
ErbB signaling pathway, organism-specific biosystemThe ErbB family of receptor tyrosine kinases (RTKs) couples binding of extracellular growth factor ligands to intracellular signaling pathways regulating diverse biologic responses, including prolife...
ErbB signaling pathway, conserved biosystem (from KEGG)
ErbB signaling pathway, conserved biosystemThe ErbB family of receptor tyrosine kinases (RTKs) couples binding of extracellular growth factor ligands to intracellular signaling pathways regulating diverse biologic responses, including prolife...

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General protein information

Preferred Names: cytoplasmic protein NCK2

Names: cytoplasmic protein NCK2

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NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001030814.1 → NP_001025985.1 cytoplasmic protein NCK2

Status: PROVISIONAL

Source sequence(s)

AJ720236

UniProtKB/TrEMBL

Q5ZK48

Related

ENSGALP00000027070, ENSGALT00000027121

Conserved Domains (2) summary

cd00174
Location:199 – 254
Blast Score: 160

SH3; Src homology 3 domains; SH3 domains bind to proline-rich ligands with moderate affinity and selectivity, preferentially to PxxP motifs; they play a role in the regulation of enzymes by intramolecular interactions, changing the subcellular localization of ...

cd10409
Location:283 – 380
Blast Score: 458

SH2_Nck2; Src homology 2 (SH2) domain found in Nck