These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
Genomic
-
NG_012265.1 RefSeqGene
- Range
- 5001..471732
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001085377.1 → NP_001078846.1 colorectal mutant cancer protein isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
- Source sequence(s)
-
AC008536, AC106750, AC126917, AK128596, BC009279, CF887436
- Consensus CDS
-
CCDS43351.1
- UniProtKB/Swiss-Prot
-
P23508
- Related
- ENSP00000386227, OTTHUMP00000222860, ENST00000408903, OTTHUMT00000370839
- Conserved Domains (4) summary
-
- cd00051
Location:39 – 95
Blast Score: 110
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- pfam10506
Location:591 – 645
Blast Score: 173
- MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome
- TIGR02168
Location:203 – 451
Blast Score: 132
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam13499
Location:45 – 96
Blast Score: 112
- EF_hand_5; EF-hand domain pair
-
NM_002387.2 → NP_002378.1 colorectal mutant cancer protein isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) has a distinct 5' UTR and 5' coding region, compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1.
- Source sequence(s)
-
AC008536, AC106750, AC126917, AK128596, BC009279, M62397
- Consensus CDS
-
CCDS4111.1
- UniProtKB/Swiss-Prot
-
P23508
- Related
- ENSP00000305617, OTTHUMP00000159017, ENST00000302475, OTTHUMT00000250736
- Conserved Domains (2) summary
-
- pfam10506
Location:401 – 455
Blast Score: 169
- MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome
- TIGR02168
Location:34 – 261
Blast Score: 113
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000005.9 Reference GRCh37.p5 Primary Assembly
- Range
- 112357796..112824527, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000137.1 Alternate HuRef
- Range
- 107537529..108007449, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)