rpl11 ribosomal protein L11 [Danio rerio] - Gene

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Summary

Official Symbol: rpl11provided by ZNC
Official Full Name: ribosomal protein L11provided by ZNC
Primary source: ZFIN:ZDB-GENE-040625-147
See related: Ensembl:ENSDARG00000043509
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as: zgc:86748

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Genomic context

Sequence :: Chromosome: 19; NC_007130.5 (45317840..45323810)

See rpl11 in MapViewer

Chromosome 19 - NC_007130.5 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ribosomal dysfunction due to the loss of L11 activates a p53-dependent checkpoint response to prevent improper embryonic development.
Title: Loss of ribosomal protein L11 affects zebrafish embryonic development through a p53-dependent apoptotic response.

Submit: New GeneRIF Correction

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Function	Evidence Code	Pubs
structural constituent of ribosome	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
embryo development	IMP Inferred from Mutant Phenotype more info	PubMed
erythrocyte differentiation	IMP Inferred from Mutant Phenotype more info
glucose homeostasis	IMP Inferred from Mutant Phenotype more info
induction of apoptosis	IMP Inferred from Mutant Phenotype more info	PubMed
translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
intracellular	IEA Inferred from Electronic Annotation more info
ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
ribosome	IEA Inferred from Electronic Annotation more info

General protein information

Preferred Names: 60S ribosomal protein L11

Names: 60S ribosomal protein L11

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NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002139.1 → NP_001002139.1 60S ribosomal protein L11

Status: PROVISIONAL

Source sequence(s)

BC071420

UniProtKB/TrEMBL

Q6IQI6

Related

ENSDARP00000063869, ENSDART00000063870

Conserved Domains (3) summary

pfam00281
Location:10 – 63
Blast Score: 163

Ribosomal_L5; Ribosomal protein L5

PTZ00156
Location:5 – 175
Blast Score: 859

PTZ00156; 60S ribosomal protein L11; Provisional

pfam00673
Location:67 – 166
Blast Score: 248

Ribosomal_L5_C; ribosomal L5P family C-terminus