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    lig3 DNA ligase III [ Drosophila melanogaster ]

    Gene ID: 41518, updated on 10-May-2012
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    Summary

    Official Symbol
    lig3provided by Flybase
    Official Full Name
    DNA ligase IIIprovided by Flybase
    Primary source
    FLYBASE:FBgn0038035
    Locus tag
    Dmel_CG17227
    Gene type
    protein coding
    RNA name
    DNA ligase III
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG17227; Dmel\CG17227; LIG3
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    Genomic context

    Location :
    87B9-87B9
    Sequence :
    Chromosome: 3R; NT_033777.2 (8224733..8227535, complement)
    See lig3 in Epigenomics, MapViewer

    Chromosome 3R - NT_033777.2Genomic Context describing neighboring genes Neighboring gene CG34402 gene product from transcript CG34402-RC Neighboring gene CG10097 gene product from transcript CG10097-RA Neighboring gene CG10096 gene product from transcript CG10096-RA Neighboring gene pseudo Neighboring gene CG11466 gene product from transcript CG11466-RB Neighboring gene CG5167 gene product from transcript CG5167-RA

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Removal of the bloom syndrome DNA helicase extends the utility of imprecise transposon excision for making null mutations in Drosophila. Witsell A, et al. Genetics, 2009 Nov. PMID 19687136.
    2. Distribution of DNA replication proteins in Drosophila cells. Easwaran HP, et al. BMC Cell Biol, 2007 Oct 15. PMID 17937809.
    3. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.
    4. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856.
    5. Combined evidence annotation of transposable elements in genome sequences. Quesneville H, et al. PLoS Comput Biol, 2005 Jul. PMID 16110336.

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:66618 BioGRID:67726 CG10157    BioGRID  PubMed Two-hybrid 
    BioGRID:66618 BioGRID:62062 CG8290    BioGRID  PubMed Two-hybrid 
    BioGRID:66618 BioGRID:61365 Cul-2    BioGRID  PubMed Two-hybrid 
    BioGRID:66618 BioGRID:63832 MEP-1    BioGRID  PubMed Two-hybrid 
    BioGRID:66618 BioGRID:62946 mus209    BioGRID  PubMed Two-hybrid 
    BioGRID:66618 BioGRID:62029 tou    BioGRID  PubMed Two-hybrid 
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    General gene information

    Pathways from BioSystems

    • Base excision repair, organism-specific biosystem (from KEGG)
      Base excision repair, organism-specific biosystemBase excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair ...
    • Base excision repair, conserved biosystem (from KEGG)
      Base excision repair, conserved biosystemBase excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair ...

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    DNA ligase (ATP) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    DNA ligation involved in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    DNA recombination IEA
    Inferred from Electronic Annotation
    more info
    		  
    DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    intracellular IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Preferred Names
    CG17227 gene product from transcript CG17227-RA
    Names
    CG17227-PA
    DNA ligase III
    lig3-PA
    ligase III
    NP_650187.2
    • unusual splice
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.2

      Range
      8224733..8227535, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141930.2 → NP_650187.2  DNA ligase III [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VG84
      Related
      FBpp0082071, FBtr0082600
      Conserved Domains (3) summary
      cd07967
      Location:460 – 598
      Blast Score: 664
      OBF_DNA_ligase_III; The Oligonucleotide/oligosaccharide binding (OB)-fold domain of ATP-dependent DNA ligase III is a DNA-binding module that is part of the catalytic core unit.
      cd07902
      Location:248 – 454
      Blast Score: 989
      Adenylation_DNA_ligase_III; Adenylation domain of DNA Ligase III
      TIGR00574
      Location:88 – 604
      Blast Score: 1113
      dnl1; DNA ligase I, ATP-dependent (dnl1)
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014297.2 AAF54801.3
    mRNA BT120103.1 ADB11088.1
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    Additional Links

    Gene LinkOut

      Supplemental Content