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Sol1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41513, updated on 11-Apr-2024

Summary

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Official Symbol
Sol1provided by FlyBase
Primary source
FLYBASE:FBgn0085431
Locus tag
Dmel_CG34402
See related
AllianceGenome:FB:FBgn0085431
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG17756; CG17793; CG31218; CG34402; CG4940; CT39356; Dmel\CG34402; dSol-1; sol-1; SOL-1
Old locus tag
CG17793; CG31218; CG4940; Dmel_CG17793; Dmel_CG31218; Dmel_CG4940
Summary
Enables channel activator activity. Involved in positive regulation of glutamatergic synaptic transmission and presynaptic modulation of chemical synaptic transmission. Located in presynaptic membrane. Is expressed in adult fat body. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See Sol1 in Genome Data Viewer
Location:
87B9-87B9; 3-52 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12386249..12402902)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8211971..8228624)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Glutathione S transferase D11 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cytochrome P450 9f3 Neighboring gene DNA ligase 3 Neighboring gene Cytochrome P450 9f2 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Conserved SOL-1 proteins regulate ionotropic glutamate receptor desensitization. Walker CS, et al. Proc Natl Acad Sci U S A, 2006 Jul 11. PMID 16818875, Free PMC Article
  2. Rapid homeostatic modulation of transsynaptic nanocolumn rings. Muttathukunnel P, et al. Proc Natl Acad Sci U S A, 2022 Nov 8. PMID 36322725, Free PMC Article
  3. The auxiliary glutamate receptor subunit dSol-1 promotes presynaptic neurotransmitter release and homeostatic potentiation. Kiragasi B, et al. Proc Natl Acad Sci U S A, 2020 Oct 13. PMID 32973097, Free PMC Article
  4. A genome-wide analysis of courting and mating responses in Drosophila melanogaster females. Lawniczak MK, et al. Genome, 2004 Oct. PMID 15499404
  5. The circadian clock interacts with metabolic physiology to influence reproductive fitness. Xu K, et al. Cell Metab, 2011 Jun 8. PMID 21641546, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The auxiliary glutamate receptor subunit dSol-1 promotes presynaptic neurotransmitter release and homeostatic potentiation.
    Title: The auxiliary glutamate receptor subunit dSol-1 promotes presynaptic neurotransmitter release and homeostatic potentiation.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables channel activator activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of synaptic transmission, glutamatergic IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in presynaptic modulation of chemical synaptic transmission IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in presynaptic membrane IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
Sol1
Names
CG34402-PC
CG34402-PD
CG34402-PE
Sol1-PC
Sol1-PD
Sol1-PE
suppressor of lurcher movement defect-1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    12386249..12402902
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001104286.2 → NP_001097756.1  Sol1, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097756.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A8JQY3, Q4V4F1
    Conserved Domains (1) summary
    cd00041
    Location:527 → 644
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

  2. NM_001300376.1 → NP_001287305.1  Sol1, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287305.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q15KK8, Q4V4F1
    Conserved Domains (1) summary
    cd00041
    Location:514 → 631
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

  3. NM_001104288.2 → NP_001097758.1  Sol1, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097758.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4V495
    Conserved Domains (1) summary
    cd00041
    Location:318 → 435
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A8JQY3 A8JQY3
Q15KK8 Q15KK8
Q4V495 Q4V495

Gene LinkOut

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