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    DNAJB3 DnaJ (Hsp40) homolog, subfamily B, member 3 [ Homo sapiens ]

    Gene ID: 414061, updated on 11-May-2012

    Summary

    Official Symbol
    DNAJB3provided by HGNC
    Official Full Name
    DnaJ (Hsp40) homolog, subfamily B, member 3provided by HGNC
    Primary source
    HGNC:32397
    See related
    HPRD:13638
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HCG3; MGC26879

    Genomic context

    Location :
    2q37
    Sequence :
    Chromosome: 2; NC_000002.11 (234651396..234652661, complement)
    See DNAJB3 in Epigenomics, MapViewer

    Chromosome 2 - NC_000002.11Genomic Context describing neighboring genes Neighboring gene diacylglycerol kinase, delta 130kDa Neighboring gene ubiquitin specific peptidase 40 Neighboring gene protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 pseudogene Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A8 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A10 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A9 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A7 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A6 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A5 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A4 Neighboring gene DnaJ (Hsp40) homolog, subfamily B, member 3 pseudogene Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A3 Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A1

    Genomic regions, transcripts, and products

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    HCG3 gene Q01844 EWSR1    HPRD  PubMed  
    BioGRID:135928 BioGRID:108431 EWSR1    BioGRID  PubMed Two-hybrid 
    BioGRID:135928 BioGRID:113164 UBC    BioGRID  PubMed Affinity Capture-MS 

    General gene information

    Markers

    Homology

    • Homologs of the DNAJB3 gene: The DNAJB3 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, A.thaliana, and rice.

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    heat shock protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    protein folding IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    dnaJ homolog subfamily B member 3
    Names
    dnaJ homolog subfamily B member 3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001001394.3NP_001001394.1  dnaJ homolog subfamily B member 3

      Status: VALIDATED

      Source sequence(s)
      AY083665
      UniProtKB/Swiss-Prot
      Q8WWF6
      Conserved Domains (1) summary
      cd06257
      Location:358
      Blast Score: 232
      DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000002.11 Reference GRCh37.p5 Primary Assembly

      Range
      234651396..234652661, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000134.1 Alternate HuRef

      Range
      226451239..226452504, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AC114812.5 AAY24024.1
    mRNA AY083665.1 AAM08934.1
    mRNA BC017590.2 AAH17590.1
    mRNA BC024013.2 AAH24013.1
    other-genetic HQ448310.1 ADQ32790.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8WWF6.1 GenPept UniProtKB/Swiss-Prot:Q8WWF6

      Supplemental Content

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