RpL3 Ribosomal protein L3 [Drosophila melanogaster] - Gene

Help top of page

Summary

Official Symbol: RpL3provided by Flybase
Official Full Name: Ribosomal protein L3provided by Flybase
Primary source: FLYBASE:FBgn0020910
Locus tag: Dmel_CG4863
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-EST:GressD4; CG4863; Dmel\CG4863; L3; rpL3

Help top of page

Genomic context

Location :: 86D8-86D8

Sequence :: Chromosome: 3R; NT_033777.2 (7047616..7050666)

See RpL3 in Epigenomics, MapViewer

Chromosome 3R - NT_033777.2 Genomic Context describing neighboring genes

Help top of page

Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

Help top of page

Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

Help top of page

Interactions

Products	Interactant	Other Gene	Source	Pubs	Description
BioGRID:66481	BioGRID:68121	BM-40-SPARC	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:58447	C901	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:66072	CG10032	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:64853	CG10154	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:65239	CG13733	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:65483	CG13813	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:68044	CG14546	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:66425	CG14684	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:61040	CG15141	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:60058	CG16947	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:60973	CG17328	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:61182	CG17568	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:64799	CG17666	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:64715	CG17826	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:66531	CG18476	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:58203	CG2116	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:58525	CG2371	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:62808	CG30115	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:58346	CG3099	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:64497	CG32036	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:59869	CG3225	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:62530	CG33017	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:77525	CG33213	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:60365	CG3769	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:64085	CG4835	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:59556	CG4896	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:65115	CG4998	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:67608	CG5346	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:60551	CG6443	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:66462	CG6621	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:60196	CG7196	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:60253	CG8349	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:59306	CG9572	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:566815	CR14499	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:65444	Grasp65	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:77555	LpR1	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:58444	Myo10A	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:68008	RASSF8	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:58607	Sec16	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:59788	Spindly	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:71867	Src64B	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:57608	TRAM	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:60532	Trim9	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:60094	Tsp	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:66091	alpha-Est7	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:60088	cup	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:65450	hale	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:64951	mRpL39	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:60845	nimC1	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:69656	ox	BioGRID	PubMed	Two-hybrid
BioGRID:66481	BioGRID:68659	toy	BioGRID	PubMed	Two-hybrid

Help top of page

General gene information

Homology

Homologs of the RpL3 gene: The RpL3 gene is conserved in human, chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, A.thaliana, rice, and P.falciparum.

Pathways from BioSystems

Cap-dependent Translation Initiation, organism-specific biosystem (from REACTOME)
Cap-dependent Translation Initiation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Cytoplasmic Ribosomal Proteins, organism-specific biosystem (from WikiPathways)
Cytoplasmic Ribosomal Proteins, organism-specific biosystem
Cytoplasmic Ribosomal Proteins
Eukaryotic Translation Elongation, organism-specific biosystem (from REACTOME)
Eukaryotic Translation Elongation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Eukaryotic Translation Initiation, organism-specific biosystem (from REACTOME)
Eukaryotic Translation Initiation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Eukaryotic Translation Termination, organism-specific biosystem (from REACTOME)
Eukaryotic Translation Termination, organism-specific biosystemcomputationally inferred pathway (not manually curated)
GTP hydrolysis and joining of the 60S ribosomal subunit, organism-specific biosystem (from REACTOME)
GTP hydrolysis and joining of the 60S ribosomal subunit, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Gene Expression, organism-specific biosystem (from REACTOME)
Gene Expression, organism-specific biosystemcomputationally inferred pathway (not manually curated)
L13a-mediated translational silencing of Ceruloplasmin expression, organism-specific biosystem (from REACTOME)
L13a-mediated translational silencing of Ceruloplasmin expression, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Metabolism of proteins, organism-specific biosystem (from REACTOME)
Metabolism of proteins, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Peptide chain elongation, organism-specific biosystem (from REACTOME)
Peptide chain elongation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Ribosome, organism-specific biosystem (from KEGG)
Ribosome, organism-specific biosystem
Ribosome
Ribosome, conserved biosystem (from KEGG)
Ribosome, conserved biosystem
Ribosome
Ribosome, eukaryotes, organism-specific biosystem (from KEGG)
Ribosome, eukaryotes, organism-specific biosystemStructural complex; Genetic information processing; Ribosome
SRP-dependent cotranslational protein targeting to membrane, organism-specific biosystem (from REACTOME)
SRP-dependent cotranslational protein targeting to membrane, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Translation, organism-specific biosystem (from REACTOME)
Translation, organism-specific biosystemcomputationally inferred pathway (not manually curated)

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
structural constituent of ribosome	ISS Inferred from Sequence or Structural Similarity more info
structural constituent of ribosome	NAS Non-traceable Author Statement more info

Process	Evidence Code	Pubs
centrosome duplication	IMP Inferred from Mutant Phenotype more info
centrosome organization	IMP Inferred from Mutant Phenotype more info
mitotic spindle elongation	IMP Inferred from Mutant Phenotype more info	PubMed
mitotic spindle organization	IMP Inferred from Mutant Phenotype more info	PubMed
translation	ISS Inferred from Sequence or Structural Similarity more info
translation	NAS Non-traceable Author Statement more info

Component	Evidence Code	Pubs
cytosolic large ribosomal subunit	ISS Inferred from Sequence or Structural Similarity more info
cytosolic large ribosomal subunit	NAS Non-traceable Author Statement more info
cytosolic ribosome	NAS Non-traceable Author Statement more info

Help top of page

General protein information

Preferred Names: CG4863 gene product from transcript CG4863-RG

Names: CG4863-PA; CG4863-PD; CG4863-PG; RpL3-PA; RpL3-PD; RpL3-PG; ribosomal protein L3

Help top of page

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NT_033777.2

Range

7047616..7050666

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_169380.2 → NP_731550.2 ribosomal protein L3, isoform G [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/Swiss-Prot

O16797

Conserved Domains (1) summary

cl00324
Location:1 – 121
Blast Score: 602

Ribosomal_L3; Ribosomal protein L3
NM_079592.3 → NP_524316.1 ribosomal protein L3, isoform A [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/Swiss-Prot

O16797

Related

FBpp0081822

Conserved Domains (1) summary

cl00324
Location:1 – 400
Blast Score: 1547

Ribosomal_L3; Ribosomal protein L3
NM_169377.2 → NP_731547.1 ribosomal protein L3, isoform D [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/Swiss-Prot

O16797

Related

FBpp0081823

Conserved Domains (1) summary

cl00324
Location:1 – 126
Blast Score: 626

Ribosomal_L3; Ribosomal protein L3