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E(var)3-9 Enhancer of variegation 3-9 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41073, updated on 27-Mar-2024

Summary

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Official Symbol
E(var)3-9provided by FlyBase
Official Full Name
Enhancer of variegation 3-9provided by FlyBase
Primary source
FLYBASE:FBgn0260243
Locus tag
Dmel_CG11971
See related
AllianceGenome:FB:FBgn0260243
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
1E9; anon-EST:fe1E9; anon1E9; Anon1E9; CG11971; Dmel\CG11971; E-var(3)9
Summary
Predicted to enable zinc ion binding activity. Involved in chromatin organization. Predicted to be active in nucleus. Is expressed in organism. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
85C1-85C1; 3-48 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8990645..8992949, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4816367..4818671, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene ichor Neighboring gene Carbonic anhydrase beta Neighboring gene Ras-related GTP binding A/B Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Large number of replacement polymorphisms in rapidly evolving genes of Drosophila. Implications for genome-wide surveys of DNA polymorphism. Schmid KJ, et al. Genetics, 1999 Dec. PMID 10581279, Free PMC Article
  2. Identification and characterization of proteins involved in nuclear organization using Drosophila GFP protein trap lines. Rohrbaugh M, et al. PLoS One, 2013. PMID 23341925, Free PMC Article
  3. Germline protein, Cup, non-cell autonomously limits migratory cell fate in Drosophila oogenesis. Saha B, et al. PLoS Genet, 2023 Feb. PMID 36791149, Free PMC Article
  4. Neutrality tests of conservative-radical amino acid changes in nuclear- and mitochondrially-encoded proteins. Rand DM, et al. Gene, 2000 Dec 30. PMID 11164043
  5. Basic leucine zipper protein Cnc-C is a substrate and transcriptional regulator of the Drosophila 26S proteasome. Grimberg KB, et al. Mol Cell Biol, 2011 Feb. PMID 21149573, Free PMC Article

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in chromatin organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
enhancer of variegation 3-9
Names
CG11971-PA
E(var)3-9-PA
anon-fast-evolving-1E9

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    8990645..8992949 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141595.3 → NP_649852.2  enhancer of variegation 3-9 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649852.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    O16044, Q9TVG9, Q9VHJ3
    Related
    FBpp0081490
    Conserved Domains (4) summary
    PHA00732
    Location:310 → 358
    PHA00732; hypothetical protein
    sd00017
    Location:281 → 303
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam07776
    Location:18 → 102
    zf-AD; Zinc-finger associated domain (zf-AD)
    pfam12756
    Location:253 → 334
    zf-C2H2_2; C2H2 type zinc-finger (2 copies)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O16044 O16044
Q7KLT3 Q7KLT3
Q8SZ92 Q8SZ92
Q9U4P6 Q9U4P6
Q9U4P7 Q9U4P7
Q9U4P8 Q9U4P8
Q9U4P9 Q9U4P9
Q9VHJ3 Q9VHJ3

Gene LinkOut

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