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    pyd3 [ Drosophila melanogaster ]

    Gene ID: 40916, updated on 9-May-2012
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    Summary

    Official Symbol
    pyd3provided by Flybase
    Primary source
    FLYBASE:FBgn0037513
    Locus tag
    Dmel_CG3027
    Gene type
    protein coding
    RNA name
    pyd3
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    betaAS; betaASase; CG3027; Dmel\CG3027
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    Genomic context

    Location :
    84D14-84D14
    Sequence :
    Chromosome: 3R; NT_033777.2 (3573635..3575798, complement)
    See pyd3 in Epigenomics, MapViewer

    Chromosome 3R - NT_033777.2Genomic Context describing neighboring genes Neighboring gene CG2616 gene product from transcript CG2616-RA Neighboring gene CG43254 gene product from transcript CG43254-RA Neighboring gene CG10919 gene product from transcript CG10919-RA Neighboring gene Serine protease 7

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Nodal points and complexity of Notch-Ras signal integration. Hurlbut GD, et al. Proc Natl Acad Sci U S A, 2009 Feb 17. PMID 19171888.
    2. A recruited protease is involved in catabolism of pyrimidines. Andersen B, et al. J Mol Biol, 2008 May 30. PMID 18448119.
    3. The crystal structure of beta-alanine synthase from Drosophila melanogaster reveals a homooctameric helical turn-like assembly. Lundgren S, et al. J Mol Biol, 2008 Apr 11. PMID 18336837.
    4. Genomic and functional studies of Drosophila sex hierarchy regulated gene expression in adult head and nervous system tissues. Goldman TD, et al. PLoS Genet, 2007 Nov. PMID 18039034.
    5. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.

    See all (16) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. The crystal structure of beta-alanine synthase (betaAS) shows a homooctameric assembly of the enzyme in the shape of a left-handed helical turn, in which tightly packed dimeric units are related by 2-fold symmetry
      Title: The crystal structure of beta-alanine synthase from Drosophila melanogaster reveals a homooctameric helical turn-like assembly.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:66104 BioGRID:62530 CG33017    BioGRID  PubMed Two-hybrid 
    BioGRID:66104 BioGRID:72482 CycK    BioGRID  PubMed Two-hybrid 
    BioGRID:66104 BioGRID:65866 Snr1    BioGRID  PubMed Two-hybrid 
    BioGRID:66104 BioGRID:66104 pyd3    BioGRID  PubMed Two-hybrid 
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    General gene information

    Homology

    • Homologs of the pyd3 gene: The pyd3 gene is conserved in human, chimpanzee, , dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, A.thaliana, and rice.

    Pathways from BioSystems

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    beta-ureidopropionase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    beta-ureidopropionase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    beta-ureidopropionase activity NAS
    Non-traceable Author Statement
    more info
    		  
    Process Evidence Code Pubs
    'de novo' pyrimidine base biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    pyrimidine base catabolic process IC
    Inferred by Curator
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    CG3027 gene product from transcript CG3027-RA
    Names
    CG3027-PA
    beta-Alanine synthase
    pyd3
    pyd3-PA
    NP_649732.1
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.2

      Range
      3573635..3575798, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141475.2 → NP_649732.1  pyd3 [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VI04
      Related
      FBpp0081276, FBtr0081780
      Conserved Domains (2) summary
      cd07587
      Location:9 – 372
      Blast Score: 1973
      ML_beta-AS; mammalian-like beta-alanine synthase (beta-AS) and similar proteins (class 5 nitrilases)
      PLN00202
      Location:9 – 385
      Blast Score: 1606
      PLN00202; beta-ureidopropionase
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    mRNA AF333187.1 AAK60520.1
    genomic AE014297.2 AAF54141.2
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VI04.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

      Supplemental Content