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CD80 CD80 molecule [ Bos taurus (cattle) ]

Gene ID: 407131, updated on 5-Mar-2024

Summary

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Official Symbol
CD80provided by VGNC
Official Full Name
CD80 moleculeprovided by VGNC
Primary source
VGNC:VGNC:27048
See related
BGD:BT24275; Ensembl:ENSBTAG00000018059
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 1 NC_037328.1 (64296500..64325064, complement)

Chromosome 1 - NC_037328.1Genomic Context describing neighboring genes Neighboring gene protein O-glucosyltransferase 1 Neighboring gene translocase of inner mitochondrial membrane domain containing 1 Neighboring gene ADP-ribosylarginine hydrolase Neighboring gene phospholipase A1 member A

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning of cattle CD80. Parsons KR, et al. Immunogenetics, 1999 Mar. PMID 9914337
  2. Expression of costimulatory molecules in the bovine corpus luteum. Cannon MJ, et al. Reprod Biol Endocrinol, 2007 Jan 31. PMID 17266770, Free PMC Article
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables coreceptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in T cell costimulation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to lipopolysaccharide IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of T cell proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of T cell proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
T-lymphocyte activation antigen CD80
Names
CD80 antigen

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001206439.1 → NP_001193368.1  T-lymphocyte activation antigen CD80

    See identical proteins and their annotated locations for NP_001193368.1

    Status: VALIDATED

    Source sequence(s)
    DY081230, NKLS02000001, Y09950
    UniProtKB/TrEMBL
    F1MHN6, O46405
    Related
    ENSBTAP00000024042.5, ENSBTAT00000024042.6
    Conserved Domains (2) summary
    cd16083
    Location:145 → 235
    IgC_CD80; Immunoglobulin constant (IgC)-like domain of antigen receptor CD80
    cl11960
    Location:40 → 142
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037328.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    64296500..64325064 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024995021.2 → XP_024850789.1  T-lymphocyte activation antigen CD80 isoform X1

    UniProtKB/TrEMBL
    A0A3S5ZP81
    Conserved Domains (2) summary
    cd16083
    Location:145 → 235
    IgC_CD80; Immunoglobulin constant (IgC)-like domain of antigen receptor CD80
    cl11960
    Location:40 → 142
    Ig; Immunoglobulin domain

  2. XM_024994968.2 → XP_024850736.1  T-lymphocyte activation antigen CD80 isoform X1

    UniProtKB/TrEMBL
    A0A3S5ZP81
    Conserved Domains (2) summary
    cd16083
    Location:145 → 235
    IgC_CD80; Immunoglobulin constant (IgC)-like domain of antigen receptor CD80
    cl11960
    Location:40 → 142
    Ig; Immunoglobulin domain
Nucleotide Protein Strain
Heading Accession and Version

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