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PPFIBP1 PPFIA binding protein 1 [ Bos taurus (cattle) ]

Gene ID: 407130, updated on 5-Mar-2024

Summary

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Official Symbol
PPFIBP1provided by VGNC
Official Full Name
PPFIA binding protein 1provided by VGNC
Primary source
VGNC:VGNC:33193
See related
BGD:BT13469; Ensembl:ENSBTAG00000004283
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
lip beta1
Orthologs
human mouse all
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Genomic context

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See PPFIBP1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
32
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (82135506..82342805, complement)

Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein S35 Neighboring gene proteasome maturation protein-like Neighboring gene RAB15 effector protein Neighboring gene chromosome 5 C12orf71 homolog Neighboring gene GTP-binding nuclear protein Ran-like Neighboring gene U6 spliceosomal RNA Neighboring gene single-pass membrane protein with coiled-coil domains 2 Neighboring gene aryl hydrocarbon receptor nuclear translocator like 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Differences between retinal and choroidal microvascular endothelial cells (MVECs) under normal and hypoxic conditions. Brylla E, et al. Exp Eye Res, 2003 Nov. PMID 14550394
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in neuromuscular junction development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in presynaptic active zone IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
liprin-beta-1
Names
liprin beta1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001304798.1 → NP_001291727.1  liprin-beta-1

    See identical proteins and their annotated locations for NP_001291727.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000005
    UniProtKB/TrEMBL
    A0A3Q1LXE1
    Related
    ENSBTAP00000062162.1, ENSBTAT00000077783.1
    Conserved Domains (7) summary
    cd09563
    Location:635 → 698
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:709 → 771
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cd09569
    Location:794 → 865
    SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
    smart00454
    Location:635 → 699
    SAM; Sterile alpha motif
    pfam01519
    Location:105 → 156
    DUF16; Protein of unknown function DUF16
    cl03075
    Location:223 → 295
    GrpE; nucleotide exchange factor GrpE
    cl23720
    Location:134 → 255
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    82135506..82342805 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024991420.2 → XP_024847188.1  liprin-beta-1 isoform X10

    Conserved Domains (4) summary
    cd09563
    Location:603 → 666
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:677 → 739
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cd09569
    Location:762 → 833
    SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
    cl25732
    Location:103 → 311
    SMC_N; RecF/RecN/SMC N terminal domain

  2. XM_024991422.2 → XP_024847190.1  liprin-beta-1 isoform X12

    Conserved Domains (5) summary
    cd09563
    Location:613 → 676
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:687 → 749
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cl15755
    Location:766 → 801
    SAM_superfamily; SAM (Sterile alpha motif )
    cl25574
    Location:102 → 520
    TOP2c; TopoisomeraseII
    cl25732
    Location:103 → 311
    SMC_N; RecF/RecN/SMC N terminal domain

  3. XM_010805397.4 → XP_010803699.1  liprin-beta-1 isoform X9

    See identical proteins and their annotated locations for XP_010803699.1

    Conserved Domains (8) summary
    cd09563
    Location:613 → 676
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:687 → 749
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cd09569
    Location:772 → 843
    SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
    smart00454
    Location:613 → 677
    SAM; Sterile alpha motif
    pfam01519
    Location:105 → 156
    DUF16; Protein of unknown function DUF16
    pfam16001
    Location:216 → 474
    DUF4775; Domain of unknown function (DUF4775)
    cl19219
    Location:229 → 314
    DUF342; Protein of unknown function (DUF342)
    cl23720
    Location:134 → 255
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

  4. XM_010805396.4 → XP_010803698.1  liprin-beta-1 isoform X6

    See identical proteins and their annotated locations for XP_010803698.1

    Conserved Domains (7) summary
    cd09563
    Location:624 → 687
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:698 → 760
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cd09569
    Location:783 → 854
    SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
    smart00454
    Location:624 → 688
    SAM; Sterile alpha motif
    pfam01519
    Location:105 → 156
    DUF16; Protein of unknown function DUF16
    cl19219
    Location:229 → 314
    DUF342; Protein of unknown function (DUF342)
    cl23720
    Location:134 → 255
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

  5. XM_024991419.2 → XP_024847187.1  liprin-beta-1 isoform X7

    Conserved Domains (5) summary
    cd09563
    Location:624 → 687
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:698 → 760
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cd09569
    Location:783 → 854
    SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
    cl25732
    Location:47 → 321
    SMC_N; RecF/RecN/SMC N terminal domain
    cl25758
    Location:216 → 485
    DUF4775; Domain of unknown function (DUF4775)

  6. XM_024991421.2 → XP_024847189.1  liprin-beta-1 isoform X11

    Conserved Domains (5) summary
    cd09563
    Location:635 → 698
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:709 → 771
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cl15755
    Location:788 → 823
    SAM_superfamily; SAM (Sterile alpha motif )
    cl25732
    Location:47 → 321
    SMC_N; RecF/RecN/SMC N terminal domain
    cl28033
    Location:341 → 634
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  7. XM_005206924.5 → XP_005206981.1  liprin-beta-1 isoform X5

    See identical proteins and their annotated locations for XP_005206981.1

    UniProtKB/TrEMBL
    F1MQQ8
    Related
    ENSBTAP00000005615.6, ENSBTAT00000005615.6
    Conserved Domains (7) summary
    cd09563
    Location:644 → 707
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:718 → 780
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cd09569
    Location:803 → 874
    SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
    smart00454
    Location:644 → 708
    SAM; Sterile alpha motif
    pfam01519
    Location:105 → 156
    DUF16; Protein of unknown function DUF16
    pfam03528
    Location:103 → 494
    Rabaptin; Rabaptin
    cl19219
    Location:203 → 281
    DUF342; Protein of unknown function (DUF342)

  8. XM_005206923.5 → XP_005206980.1  liprin-beta-1 isoform X3

    See identical proteins and their annotated locations for XP_005206980.1

    Conserved Domains (7) summary
    cd09563
    Location:655 → 718
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:729 → 791
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cd09569
    Location:814 → 885
    SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
    smart00454
    Location:655 → 719
    SAM; Sterile alpha motif
    pfam01519
    Location:105 → 156
    DUF16; Protein of unknown function DUF16
    pfam03528
    Location:103 → 494
    Rabaptin; Rabaptin
    cl19219
    Location:203 → 281
    DUF342; Protein of unknown function (DUF342)

  9. XM_010805394.4 → XP_010803696.1  liprin-beta-1 isoform X2

    See identical proteins and their annotated locations for XP_010803696.1

    Conserved Domains (7) summary
    cd09563
    Location:656 → 719
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:730 → 792
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cd09569
    Location:815 → 886
    SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
    smart00454
    Location:656 → 720
    SAM; Sterile alpha motif
    pfam01519
    Location:105 → 156
    DUF16; Protein of unknown function DUF16
    pfam03528
    Location:103 → 476
    Rabaptin; Rabaptin
    cl19219
    Location:203 → 281
    DUF342; Protein of unknown function (DUF342)

  10. XM_010805395.4 → XP_010803697.1  liprin-beta-1 isoform X4

    See identical proteins and their annotated locations for XP_010803697.1

    Conserved Domains (7) summary
    cd09563
    Location:655 → 718
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:729 → 791
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cd09569
    Location:814 → 885
    SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
    smart00454
    Location:655 → 719
    SAM; Sterile alpha motif
    pfam01519
    Location:105 → 156
    DUF16; Protein of unknown function DUF16
    pfam03528
    Location:103 → 505
    Rabaptin; Rabaptin
    cl19219
    Location:203 → 281
    DUF342; Protein of unknown function (DUF342)

  11. XM_015471218.3 → XP_015326704.1  liprin-beta-1 isoform X8

    Conserved Domains (7) summary
    cd09563
    Location:666 → 729
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:740 → 802
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    smart00454
    Location:666 → 730
    SAM; Sterile alpha motif
    pfam01519
    Location:105 → 156
    DUF16; Protein of unknown function DUF16
    pfam03528
    Location:103 → 505
    Rabaptin; Rabaptin
    cl15755
    Location:819 → 854
    SAM_superfamily; SAM (Sterile alpha motif )
    cl19219
    Location:203 → 281
    DUF342; Protein of unknown function (DUF342)

  12. XM_010805392.4 → XP_010803694.1  liprin-beta-1 isoform X1

    See identical proteins and their annotated locations for XP_010803694.1

    Conserved Domains (7) summary
    cd09563
    Location:666 → 729
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:740 → 802
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cd09569
    Location:825 → 896
    SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
    smart00454
    Location:666 → 730
    SAM; Sterile alpha motif
    pfam01519
    Location:105 → 156
    DUF16; Protein of unknown function DUF16
    pfam03528
    Location:103 → 505
    Rabaptin; Rabaptin
    cl19219
    Location:203 → 281
    DUF342; Protein of unknown function (DUF342)

  13. XM_015471217.3 → XP_015326703.1  liprin-beta-1 isoform X1

    Conserved Domains (7) summary
    cd09563
    Location:666 → 729
    SAM_liprin-beta1,2_repeat1; SAM domain of liprin-beta1,2 proteins repeat 1
    cd09566
    Location:740 → 802
    SAM_liprin-beta1,2_repeat2; SAM domain of liprin-beta1,2 proteins repeat 2
    cd09569
    Location:825 → 896
    SAM_liprin-beta1,2_repeat3; SAM domain of liprin-beta proteins repeat 3
    smart00454
    Location:666 → 730
    SAM; Sterile alpha motif
    pfam01519
    Location:105 → 156
    DUF16; Protein of unknown function DUF16
    pfam03528
    Location:103 → 505
    Rabaptin; Rabaptin
    cl19219
    Location:203 → 281
    DUF342; Protein of unknown function (DUF342)

  14. XM_059886140.1 → XP_059742123.1  liprin-beta-1 isoform X1

Nucleotide Protein Strain
Heading Accession and Version

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