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    NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha [ Sus scrofa (pig) ]

    Gene ID: 406188, updated on 15-Jun-2013
    Gene symbol
    NFKBIA
    Gene description
    nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus
    Also known as
    IKBA; ECI-6/IKBA
    Location :
    7q15-q21; 7
    Sequence :
    Chromosome: 7; NC_010449.4 (69417685..69420320)
    See NFKBIA in MapViewer

    Chromosome 7 - NC_010449.4Genomic Context describing neighboring genes Neighboring gene insulinoma-associated protein 2-like Neighboring gene ferritin heavy chain-like Neighboring gene proteasome (prosome, macropain) subunit, alpha type, 6 Neighboring gene mitochondrial ribonuclease P protein 3-like

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. Species-specific variation in RELA underlies differences in NF-κB activity: a potential role in African swine fever pathogenesis. Palgrave CJ, et al. J Virol, 2011 Jun. PMID 21450812.
    2. Comparative analysis of protein coding sequences from human, mouse and the domesticated pig. Jørgensen FG, et al. BMC Biol, 2005 Jan 28. PMID 15679890.
    3. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463.
    4. Assignment of the porcine IKBA gene (IkappaBalpha) encoding a cytoplasmic inhibitor of the NF-kappaB to chromosome 7q15-q21 by FISH. Musilová P, et al. Mamm Genome, 1996 Apr. PMID 8661710.
    5. Intron-exon structure of the porcine I kappa B alpha-encoding gene. de Martin R, et al. Gene, 1995 Jan 23. PMID 7835710.

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction

    Markers

    Genotypes

    Homology

    Preferred Names
    NF-kappa-B inhibitor alpha
    Names
    NF-kappa-B inhibitor alpha
    ECI-6
    ikB-alpha
    ikappaBalpha
    I-kappa-B-alpha

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005150.1 → NP_001005150.1  NF-kappa-B inhibitor alpha

      Status: PROVISIONAL

      Source sequence(s)
      Z35483
      UniProtKB/Swiss-Prot
      Q08353
      Conserved Domains (3) summary
      cd00204
      Location:105 – 237
      Blast Score: 276
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      COG0666
      Location:60 – 165
      Blast Score: 138
      Arp; FOG: Ankyrin repeat [General function prediction only]
      pfam12796
      Location:115 – 246
      Blast Score: 198
      Ank_2; Ankyrin repeats (3 copies)

    RefSeqs of Annotated Genomes: Build 4.1

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa10.2 Primary Assembly

    Genomic

    1. NC_010449.4 Reference Sscrofa10.2 Primary Assembly

      Range
      69417685..69420320
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    genomic A38490.1 CAA02379.1
    genomic CT797470.4 (146241..148878) None
    genomic FP326714.2 (149010..151645) None
    genomic Z35483.1 CAA84619.1
    mRNA AK233732.1 None
    mRNA AK239662.1 None
    mRNA AY609599.1 None
    mRNA FN421467.1 CAZ65750.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08353.1 GenPept UniProtKB/Swiss-Prot:Q08353

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Miscellaneous

      Supplemental Content

      Table of contents

      Related information

      • BioProjects
        BioProjects related to a gene
      • BioSystems
        BioSystems
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • Full text in PMC
        PMC links
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • Genome
        Genome records having the gene annotated on corresponding genomic reference sequence.
      • Map Viewer
        These links are maintained by the Map Viewer group and are provided when a GeneID is annotated on a map for the same species.
      • Nucleotide
        Link to related Nucleotide entry
      • Probe
        Related Probe entry
      • Protein
        Link to related protein entry
      • PubChem Compound
        PubChem Compounds
      • PubChem Substance
        PubChem Substances
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • SNP
        Related SNP records
      • SNP: GeneView
        SNPs linked from GeneView
      • Taxonomy
        Link to related taxonomy entry
      • UniGene
        Links are provided between Gene and UniGene when both databases calculate links to the same mRNA record (gi).
      • UniSTS
        Related UniSTS records

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