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HDAC1 histone deacetylase 1 [ Bos taurus (cattle) ]

Gene ID: 404126, updated on 22-Nov-2014
Official Symbol
HDAC1
Official Full Name
histone deacetylase 1
Locus tag
BOS_2162
See related
BGD:BT24774; Ensembl:ENSBTAG00000012698
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
See HDAC1 in MapViewer
Location:
chromosome: 2
Exon count:
15
Annotation release Status Assembly Chr Location
103 current Bos_taurus_UMD_3.1 (GCF_000003055.4) 2 AC_000159.1 (122055987..122087843, complement)

Chromosome 2 - AC_000159.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC614396 Neighboring gene testis-specific serine kinase 3 Neighboring gene MARCKS-like 1 Neighboring gene lymphocyte-specific protein tyrosine kinase Neighboring gene family with sequence similarity 167, member B

Markers

Homology

Clone Names

  • MGC127235

Gene Ontology Provided by GOA

Function Evidence Code Pubs
NAD-dependent histone deacetylase activity (H3-K14 specific) IEA
Inferred from Electronic Annotation
more info
 
NAD-dependent histone deacetylase activity (H3-K18 specific) IEA
Inferred from Electronic Annotation
more info
 
NAD-dependent histone deacetylase activity (H3-K9 specific) IEA
Inferred from Electronic Annotation
more info
 
NAD-dependent histone deacetylase activity (H4-K16 specific) IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II core promoter proximal region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II distal enhancer sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II repressing transcription factor binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 
activating transcription factor binding IEA
Inferred from Electronic Annotation
more info
 
core promoter binding IEA
Inferred from Electronic Annotation
more info
 
deacetylase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
histone deacetylase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
histone deacetylase binding IEA
Inferred from Electronic Annotation
more info
 
nucleosomal DNA binding IEA
Inferred from Electronic Annotation
more info
 
transcription regulatory region sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
ATP-dependent chromatin remodeling IEA
Inferred from Electronic Annotation
more info
 
circadian regulation of gene expression ISS
Inferred from Sequence or Structural Similarity
more info
 
histone H3 deacetylation IEA
Inferred from Electronic Annotation
more info
 
histone H3-K9 modification IEA
Inferred from Electronic Annotation
more info
 
histone H4 deacetylation ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation by host of viral transcription IEA
Inferred from Electronic Annotation
more info
 
negative regulation of androgen receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription, DNA-templated ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of cell proliferation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of receptor biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
NuRD complex IEA
Inferred from Electronic Annotation
more info
 
Sin3 complex IEA
Inferred from Electronic Annotation
more info
 
cytosol IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
histone deacetylase 1
Names
histone deacetylase 1
HD1
NP_001032521.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037444.2NP_001032521.1  histone deacetylase 1

    See proteins identical to NP_001032521.1

    Status: PROVISIONAL

    Source sequence(s)
    BC108088
    UniProtKB/Swiss-Prot
    Q32PJ8
    Related
    ENSBTAP00000016877, ENSBTAT00000016877
    Conserved Domains (1) summary
    cd10010
    Location:4374
    HDAC1; Histone deacetylase 1 (HDAC1)

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 103

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bos_taurus_UMD_3.1 Primary Assembly

Genomic

  1. AC_000159.1 

    Range
    122055987..122087843
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005202895.1XP_005202952.1  

    Conserved Domains (1) summary
    cl17011
    Location:1345
    Arginase_HDAC; Arginase-like and histone-like hydrolases

Alternate Btau_4.6.1

Genomic

  1. NC_007300.5 

    Range
    126786130..126818071
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)