CG11249 [Drosophila melanogaster] - Gene

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Summary

Official Symbol: CG11249provided by Flybase
Primary source: FLYBASE:FBgn0037115
Locus tag: Dmel_CG11249
Gene type: protein coding
RNA name: CG11249
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: Dmel\CG11249

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Genomic context

Location :: 78E3-78E3

Sequence :: Chromosome: 3L; NT_037436.3 (21665239..21667618)

See CG11249 in Epigenomics, MapViewer

Chromosome 3L - NT_037436.3 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

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Interactions

Products	Interactant	Other Gene	Source	Pubs	Description
BioGRID:65651	BioGRID:57628	CG11380	BioGRID	PubMed	Two-hybrid
BioGRID:65651	BioGRID:66601	CG3942	BioGRID	PubMed	Two-hybrid
BioGRID:65651	BioGRID:68777	sol	BioGRID	PubMed	Two-hybrid

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General gene information

Pathways from BioSystems

Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate, organism-specific biosystem (from KEGG)
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate, organism-specific biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate, conserved biosystem (from KEGG)
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate, conserved biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Glycolysis / Gluconeogenesis, organism-specific biosystem (from KEGG)
Glycolysis / Gluconeogenesis, organism-specific biosystemGlycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabol...
Glycolysis / Gluconeogenesis, conserved biosystem (from KEGG)
Glycolysis / Gluconeogenesis, conserved biosystemGlycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabol...
Glycolysis, core module involving three-carbon compounds, organism-specific biosystem (from KEGG)
Glycolysis, core module involving three-carbon compounds, organism-specific biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Glycolysis, core module involving three-carbon compounds, conserved biosystem (from KEGG)
Glycolysis, core module involving three-carbon compounds, conserved biosystemPathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
Metabolic pathways, organism-specific biosystem (from KEGG)
Metabolic pathways, organism-specific biosystem
Metabolic pathways
Purine metabolism, organism-specific biosystem (from KEGG)
Purine metabolism, organism-specific biosystem
Purine metabolism
Purine metabolism, conserved biosystem (from KEGG)
Purine metabolism, conserved biosystem
Purine metabolism
Pyruvate metabolism, organism-specific biosystem (from KEGG)
Pyruvate metabolism, organism-specific biosystem
Pyruvate metabolism
Pyruvate metabolism, conserved biosystem (from KEGG)
Pyruvate metabolism, conserved biosystem
Pyruvate metabolism

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
magnesium ion binding	IEA Inferred from Electronic Annotation more info
potassium ion binding	IEA Inferred from Electronic Annotation more info
pyruvate kinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
glycolysis	IEA Inferred from Electronic Annotation more info

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General protein information

Preferred Names: CG11249 gene product from transcript CG11249-RA

Names: CG11249; CG11249-PA

NP_649346.1

EC 2.7.1.40

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NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NT_037436.3

Range

21665239..21667618

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_141089.1 → NP_649346.1 CG11249 [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/TrEMBL

Q9VNZ9

Related

FBpp0078083, FBtr0078429

Conserved Domains (1) summary

cl09155
Location:485 – 604
Blast Score: 125

Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...