Grasp65 [Drosophila melanogaster] - Gene

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Summary

Official Symbol: Grasp65provided by Flybase
Primary source: FLYBASE:FBgn0036919
Locus tag: Dmel_CG7809
Gene type: protein coding
RNA name: Grasp65
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG7809; dgrasp; dGRASP; dGrasp65; Dmel\CG7809

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Genomic context

Location :: 76D5-76D5

Sequence :: Chromosome: 3L; NT_037436.3 (19918161..19919979)

See Grasp65 in Epigenomics, MapViewer

Chromosome 3L - NT_037436.3 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

dGRASP-mediated noncanonical secretion route allows for developmental regulation of integrin function upon epithelial remodeling.
Title: dGRASP-mediated noncanonical integrin secretion is required for Drosophila epithelial remodeling.

Submit: New GeneRIF Correction

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Interactions

Products	Interactant	Other Gene	Source	Pubs	Description
BioGRID:65444	BioGRID:60404	CG13124	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:64586	CG14154	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:66513	CG14708	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:58000	CG15771	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:64799	CG17666	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:65924	CG2046	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:57666	CG32810	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:77512	CG33123	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:63192	CG3927	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:78221	CG40042	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:67177	CG7357	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:60254	CG8292	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:66807	CG9624	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:59687	CG9894	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:62899	Elongin-C	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:63053	Glycogenin	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:59747	Hydr2	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:71956	Mbs	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:1073063	Pif1A	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:69024	RFeSP	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:62307	RN-tre	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:72726	RecQ4	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:625077	Rgk3	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:67782	Rox8	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:66481	RpL3	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:68867	RpS15Aa	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:68606	RpS3A	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:67596	Rpn7	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:58982	Sep4	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:73152	Tango11	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:57723	Unc-76	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:60620	ab	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:59819	ed	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:62151	fra	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:58716	inaE	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:67507	lbl	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:68000	msi	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:66305	mura	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:63008	otp	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:62356	phyl	BioGRID	PubMed	Two-hybrid
BioGRID:65444	BioGRID:66738	yrt	BioGRID	PubMed	Two-hybrid

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General gene information

Homology

Homologs of the Grasp65 gene: The Grasp65 gene is conserved in human, chimpanzee, , dog, cow, mouse, rat, chicken, zebrafish, and mosquito.

Pathways from BioSystems

Cell Cycle, organism-specific biosystem (from REACTOME)
Cell Cycle, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Cell Cycle, Mitotic, organism-specific biosystem (from REACTOME)
Cell Cycle, Mitotic, organism-specific biosystemcomputationally inferred pathway (not manually curated)
DNA Replication, organism-specific biosystem (from REACTOME)
DNA Replication, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Golgi Cisternae Pericentriolar Stack Reorganization, organism-specific biosystem (from REACTOME)
Golgi Cisternae Pericentriolar Stack Reorganization, organism-specific biosystemcomputationally inferred pathway (not manually curated)
M Phase, organism-specific biosystem (from REACTOME)
M Phase, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Mitotic M-M/G1 phases, organism-specific biosystem (from REACTOME)
Mitotic M-M/G1 phases, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Mitotic Prophase, organism-specific biosystem (from REACTOME)
Mitotic Prophase, organism-specific biosystemcomputationally inferred pathway (not manually curated)

Gene Ontology Provided by FlyBase

Process	Evidence Code	Pubs
Golgi organization	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
Golgi membrane	ISS Inferred from Sequence or Structural Similarity more info
Golgi stack	IDA Inferred from Direct Assay more info	PubMed
Golgi-associated vesicle	IDA Inferred from Direct Assay more info	PubMed
endoplasmic reticulum	IDA Inferred from Direct Assay more info	PubMed

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General protein information

Preferred Names: CG7809 gene product from transcript CG7809-RA

Names: CG7809-PA; Grasp65; Grasp65-PA

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NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NT_037436.3

Range

19918161..19919979

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_140903.1 → NP_649160.1 Grasp65 [Drosophila melanogaster]

Status: REVIEWED

UniProtKB/TrEMBL

Q9VW57

Related

FBpp0074664, FBtr0074895

Conserved Domains (2) summary

cd00989
Location:9 – 86
Blast Score: 107

PDZ_metalloprotease; PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ ...

cl00117
Location:71 – 205
Blast Score: 628

PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...