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    CG7757 [ Drosophila melanogaster ]

    Gene ID: 40172, updated on 8-Jan-2012
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    Summary

    Official Symbol
    CG7757provided by Flybase
    Primary source
    FLYBASE:FBgn0036915
    Locus tag
    Dmel_CG7757
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7757; PRPF3
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    Genomic context

    Location :
    76D4-76D4
    Sequence :
    Chromosome: 3L; NT_037436.3 (19903403..19905604)
    See CG7757 in Epigenomics, MapViewer

    Chromosome 3L - NT_037436.3Genomic Context describing neighboring genes Neighboring gene CG8334 gene product from transcript CG8334-RA Neighboring gene CG8103 gene product from transcript CG8103-RA Neighboring gene CG32217 gene product from transcript CG32217-RB Neighboring gene ncRNA Neighboring gene CG8025 gene product from transcript CG8025-RA Neighboring gene CG7762 gene product from transcript CG7762-RA Neighboring gene CG8013 gene product from transcript CG8013-RA

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Herold N, et al. Mol Cell Biol, 2009 Jan. PMID 18981222.
    2. Identification of Drosophila mitotic genes by combining co-expression analysis and RNA interference. Somma MP, et al. PLoS Genet, 2008 Jul 18. PMID 18797514.
    3. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.
    4. The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Smith CD, et al. Science, 2007 Jun 15. PMID 17569856.
    5. A gain-of-function screen identifying genes required for vein formation in the Drosophila melanogaster wing. Molnar C, et al. Genetics, 2006 Nov. PMID 16980395.

    See all (14) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:65440 BioGRID:59928 Bsg25D    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:67967 CG10513    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:67789 CG10694    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:63934 CG1120    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:63151 CG11275    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:58865 CG11679    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:63355 CG12491    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:65162 CG13032    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:60468 CG13138    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:63581 CG13405    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:64711 CG14126    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:66938 CG14868    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:63098 CG15676    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:63701 CG2199    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:58346 CG3099    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:63284 CG3162    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:64754 CG32100    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:59866 CG3294    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:58073 CG3342    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:66450 CG4570    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:60418 CG4709    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:65128 CG4877    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:62713 CG5009    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:64115 CG5537    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:66919 CG6276    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:67535 CG6569    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:67216 CG7131    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:66687 CG7518    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:65440 CG7757    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:60264 CG7818    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:63738 CG7967    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:62428 CG8079    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:66324 CG8319    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:61797 CG8801    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:66150 CG9636    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:61931 Git    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:67047 Gyc-89Db    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:65272 MED19    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:64242 MED4    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:66772 Nsf2    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:68619 Rad23    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:64432 Srp68    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:68427 Sry-alpha    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:58942 U2af50    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:62251 cnn    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:61072 elfless    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:67689 fzo    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:63037 king-tubby    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:62647 l(2)k01209    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:58172 p115    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:63711 pUf68    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:62415 pcs    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:61516 pgant3    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:64196 ple    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:68911 sip1    BioGRID  PubMed Two-hybrid 
    BioGRID:65440 BioGRID:60129 sip2    BioGRID  PubMed Two-hybrid 
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    General gene information

    Homology

    • Homologs of the CG7757 gene: The CG7757 gene is conserved in human, chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, S.pombe, M.grisea, N.crassa, A.thaliana, and rice.

    Pathways from BioSystems

    • Spliceosome, organism-specific biosystem (from KEGG)
      Spliceosome, organism-specific biosystemAfter transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, th...
    • Spliceosome, conserved biosystem (from KEGG)
      Spliceosome, conserved biosystemAfter transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, th...
    • Spliceosome, U4/U6.U5 tri-snRNP, organism-specific biosystem (from KEGG)
      Spliceosome, U4/U6.U5 tri-snRNP, organism-specific biosystemStructural complex; Genetic information processing; Spliceosome
    • mRNA processing, organism-specific biosystem (from WikiPathways)
      mRNA processing, organism-specific biosystemThis process describes the conversion of precursor messenger RNA into mature messenger RNA (mRNA). The pre-mRNA molecule undergoes three main modifications. These modifications are 5' capping, 3' pol...

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    nuclear mRNA splicing, via spliceosome IC
    Inferred by Curator
    more info
    		 PubMed 
    nuclear mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    regulation of chromatin silencing IMP
    Inferred from Mutant Phenotype
    more info
    		  
    Component Evidence Code Pubs
    U4 snRNP ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    U6 snRNP ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    precatalytic spliceosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    small nuclear ribonucleoprotein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    spliceosomal complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    CG7757 gene product from transcript CG7757-RA
    Names
    CG7757
    CG7757-PA
    CG7757-PB
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.3

      Range
      19903403..19905604
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140899.2 → NP_649156.1  CG7757, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VW52
      Related
      FBpp0074660, FBtr0074891
      Conserved Domains (2) summary
      pfam06544
      Location:464 – 586
      Blast Score: 355
      DUF1115; Protein of unknown function (DUF1115)
      pfam08572
      Location:226 – 442
      Blast Score: 648
      PRP3; pre-mRNA processing factor 3 (PRP3)

    2. NM_168825.2 → NP_730463.1  CG7757, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MRG6
      Related
      FBpp0074661, FBtr0074892
      Conserved Domains (2) summary
      pfam06544
      Location:394 – 516
      Blast Score: 353
      DUF1115; Protein of unknown function (DUF1115)
      pfam08572
      Location:156 – 372
      Blast Score: 643
      PRP3; pre-mRNA processing factor 3 (PRP3)
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014296.4 AAF49097.1
    mRNA AY119640.1 AAM50294.1
    genomic AE014296.4 AAN11640.1
    Protein Accession Links
    GenePept Link UniProtKB Link
    Q9VW52.1 GenPept
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    Additional Links

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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