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    Su(Tpl) [ Drosophila melanogaster ]

    Gene ID: 40171, updated on 8-Jan-2012
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    Summary

    Official Symbol
    Su(Tpl)provided by Flybase
    Primary source
    FLYBASE:FBgn0014037
    Locus tag
    Dmel_CG32217
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    0854/01; CG32217; CG8037; CR32216; dELL; Dmel\CG32217; Ell; ELL; l (3)76BD; l(3)76BDs; l(3)S000606; l(3)S085401; SR3-4A; SS3-4; SY3-1
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    Genomic context

    Location :
    76D3-76D4; 3-46.5 cM
    Sequence :
    Chromosome: 3L; NT_037436.3 (19884505..19902500, complement)
    See Su(Tpl) in Epigenomics, MapViewer

    Chromosome 3L - NT_037436.3Genomic Context describing neighboring genes Neighboring gene Rab-protein 8 Neighboring gene CG8334 gene product from transcript CG8334-RA Neighboring gene CG8103 gene product from transcript CG8103-RA Neighboring gene ncRNA Neighboring gene CG7757 gene product from transcript CG7757-RA Neighboring gene CG8025 gene product from transcript CG8025-RA Neighboring gene CG7762 gene product from transcript CG7762-RA

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. A screen for modifiers of notch signaling uncovers Amun, a protein with a critical role in sensory organ development. Shalaby NA, et al. Genetics, 2009 Aug. PMID 19448274.
    2. Comparative analysis of argonaute-dependent small RNA pathways in Drosophila. Zhou R, et al. Mol Cell, 2008 Nov 21. PMID 19026789.
    3. Regulation of the transcriptional activity of poised RNA polymerase II by the elongation factor ELL. Smith ER, et al. Proc Natl Acad Sci U S A, 2008 Jun 24. PMID 18562276.
    4. A gain-of-function suppressor screen for genes involved in dorsal-ventral boundary formation in the Drosophila wing. Bejarano F, et al. Genetics, 2008 Jan. PMID 18202376.
    5. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867.

    See all (34) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. elongation factor ELL protein regulates the transcription activvity of RNA polymerase II
      Title: Regulation of the transcriptional activity of poised RNA polymerase II by the elongation factor ELL.
    2. Drosophila ELL has an essential activity in development distinct from its role as an RNA polymerase II elongation factor
      Title: Mutational analysis of an RNA polymerase II elongation factor in Drosophila melanogaster.
    3. an essential RNA polymerase II elongation factor with a general role in development
      Title: dELL is an essential RNA polymerase II elongation factor with a general role in development.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:65439 BioGRID:57823 N    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:65439 BioGRID:66301 Ras85D    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression 
    BioGRID:65439 BioGRID:59621 aop    BioGRID  PubMed Phenotypic Enhancement; Phenotypic Suppression 
    BioGRID:65439 BioGRID:69119 ct    BioGRID  PubMed Phenotypic Enhancement 
    BioGRID:65439 BioGRID:58454 sev    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:65439 BioGRID:65183 sina    BioGRID  PubMed Phenotypic Suppression 
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    General gene information

    Homology

    Pathways from BioSystems

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    regulation of DNA-dependent transcription in response to stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    transcription elongation from RNA polymerase II promoter IEA
    Inferred from Electronic Annotation
    more info
    		  
    wing disc dorsal/ventral pattern formation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    polytene chromosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    transcription elongation factor complex IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Preferred Names
    CG32217 gene product from transcript CG32217-RB
    Names
    CG32217-PA
    CG32217-PB
    Su(Tpl)
    Su(Tpl)-PA
    Su(Tpl)-PB
    suppressor of GMR-sina 3-4
    suppressor of triplolethal
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.3

      Range
      19884505..19902500, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001170006.1 → NP_001163477.1  Su(Tpl), isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VW51
      Related
      FBpp0291257, FBtr0302047
      Conserved Domains (2) summary
      pfam07303
      Location:833 – 936
      Blast Score: 317
      Occludin_ELL; Occludin homology domain
      pfam10390
      Location:15 – 185
      Blast Score: 371
      ELL; RNA polymerase II elongation factor ELL

    2. NM_140898.4 → NP_649155.3  Su(Tpl), isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VW51
      Related
      FBpp0074689, FBtr0074920
      Conserved Domains (2) summary
      pfam07303
      Location:833 – 936
      Blast Score: 317
      Occludin_ELL; Occludin homology domain
      pfam10390
      Location:15 – 185
      Blast Score: 371
      ELL; RNA polymerase II elongation factor ELL
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    mRNA BT058015.1 ACM16731.1
    genomic AE014296.4 ACZ94748.1
    mRNA BT050407.1 ACI88733.1
    genomic AE014296.4 AAF49098.3
    Protein Accession Links
    GenePept Link UniProtKB Link
    AAF49098.1 GenPept
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    Additional Links

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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