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    verm vermiform [ Drosophila melanogaster ]

    Gene ID: 40149, updated on 10-May-2012
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    Summary

    Official Symbol
    vermprovided by Flybase
    Official Full Name
    vermiformprovided by Flybase
    Primary source
    FLYBASE:FBgn0261341
    Locus tag
    Dmel_CG8756
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8756; DmCDA2; Dmel\CG8756; hlm; l(3)76BDx; LCBP1; N63; Verm
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    Genomic context

    Location :
    76C2-76C3
    Sequence :
    Chromosome: 3L; NT_037436.3 (19683133..19688356, complement)
    See verm in Epigenomics, MapViewer

    Chromosome 3L - NT_037436.3Genomic Context describing neighboring genes Neighboring gene CG8765 gene product from transcript CG8765-RA Neighboring gene G protein beta-subunit 76C Neighboring gene serpentine Neighboring gene transient receptor potential mucolipin

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. GlycoFly: a database of Drosophila N-linked glycoproteins identified using SPEG--MS techniques. Baycin-Hizal D, et al. J Proteome Res, 2011 Jun 3. PMID 21480662.
    2. Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. Blanco E, et al. BMC Dev Biol, 2010 Sep 2. PMID 20813047.
    3. Trafficking through COPII stabilises cell polarity and drives secretion during Drosophila epidermal differentiation. Norum M, et al. PLoS One, 2010 May 24. PMID 20520821.
    4. Molecular genetic analysis of Chd3 and polytene chromosome region 76B-D in Drosophila melanogaster. Cooper MT, et al. Genetics, 2010 Jul. PMID 20439780.
    5. The Drosophila Claudin Kune-kune is required for septate junction organization and tracheal tube size control. Nelson KS, et al. Genetics, 2010 Jul. PMID 20407131.

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Serpentine (serp) and Vermiform (verm) encode similar proteins with an LDL-receptor ligand binding motif and chitin binding and deacetylation domains and are required for the normal fibrillar structure of chitin.
      Title: serpentine and vermiform encode matrix proteins with chitin binding and deacetylation domains that limit tracheal tube length in Drosophila.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:65419 BioGRID:68286 Doa    BioGRID  PubMed Two-hybrid 
    BioGRID:65419 BioGRID:64396 Zasp66    BioGRID  PubMed Two-hybrid 
    BioGRID:65419 BioGRID:68605 ci    BioGRID  PubMed Two-hybrid 
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    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    chitin binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    chitin deacetylase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    low-density lipoprotein receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    chitin metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    dorsal trunk growth, open tracheal system IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    open tracheal system development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    regulation of tube length, open tracheal system IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    trachea morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    visual behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
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    General protein information

    Preferred Names
    CG8756 gene product from transcript CG8756-RD
    Names
    CG8756-PB
    CG8756-PC
    CG8756-PD
    CG8756-PE
    CG8756-PF
    CG8756-PG
    LDLa domain containing chitin binding protein 1
    helmsman
    verm-PB
    verm-PC
    verm-PD
    verm-PE
    verm-PF
    verm-PG
    vermiform
    NP_001163469.1
    NP_001163470.1
    NP_649142.1
    NP_730441.1
    NP_730442.2
    NP_730443.1
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.3

      Range
      19683133..19688356, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140885.2 → NP_649142.1  vermiform, isoform D [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IQU1
      Related
      FBpp0074725, FBtr0074957
      Conserved Domains (3) summary
      cd00112
      Location:108 – 142
      Blast Score: 111
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      cd10974
      Location:183 – 458
      Blast Score: 1235
      CE4_CDA_like_1; Putative catalytic domain of chitin deacetylase-like proteins with additional chitin-binding peritrophin-A domain (ChBD) and/or a low-density lipoprotein receptor class A domain (LDLa)
      cl02629
      Location:33 – 88
      Blast Score: 116
      CBM_14; Chitin binding Peritrophin-A domain

    2. NM_168808.2 → NP_730441.1  vermiform, isoform C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VW31
      Related
      FBpp0074724, FBtr0074956
      Conserved Domains (3) summary
      cd00112
      Location:114 – 148
      Blast Score: 111
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      cd10974
      Location:189 – 464
      Blast Score: 1235
      CE4_CDA_like_1; Putative catalytic domain of chitin deacetylase-like proteins with additional chitin-binding peritrophin-A domain (ChBD) and/or a low-density lipoprotein receptor class A domain (LDLa)
      cl02629
      Location:33 – 94
      Blast Score: 94
      CBM_14; Chitin binding Peritrophin-A domain

    3. NM_001169999.1 → NP_001163470.1  vermiform, isoform F [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JI41
      Related
      FBpp0291539, FBtr0302334
      Conserved Domains (1) summary
      cl02629
      Location:33 – 94
      Blast Score: 89
      CBM_14; Chitin binding Peritrophin-A domain

    4. NM_168810.2 → NP_730443.1  vermiform, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VW30
      Related
      FBpp0074722, FBtr0074954
      Conserved Domains (3) summary
      cd00112
      Location:132 – 166
      Blast Score: 111
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      cd10974
      Location:207 – 482
      Blast Score: 1234
      CE4_CDA_like_1; Putative catalytic domain of chitin deacetylase-like proteins with additional chitin-binding peritrophin-A domain (ChBD) and/or a low-density lipoprotein receptor class A domain (LDLa)
      cl02629
      Location:57 – 112
      Blast Score: 117
      CBM_14; Chitin binding Peritrophin-A domain

    5. NM_001169998.1 → NP_001163469.1  vermiform, isoform E [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JI40
      Related
      FBpp0291538, FBtr0302333
      Conserved Domains (3) summary
      cd00112
      Location:138 – 172
      Blast Score: 111
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      cd10974
      Location:213 – 488
      Blast Score: 1234
      CE4_CDA_like_1; Putative catalytic domain of chitin deacetylase-like proteins with additional chitin-binding peritrophin-A domain (ChBD) and/or a low-density lipoprotein receptor class A domain (LDLa)
      cl02629
      Location:57 – 118
      Blast Score: 95
      CBM_14; Chitin binding Peritrophin-A domain

    6. NM_168809.2 → NP_730442.2  vermiform, isoform G [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IQU1
      Related
      FBpp0291540, FBtr0302335
      Conserved Domains (3) summary
      cd00112
      Location:108 – 142
      Blast Score: 111
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      cd10974
      Location:183 – 458
      Blast Score: 1235
      CE4_CDA_like_1; Putative catalytic domain of chitin deacetylase-like proteins with additional chitin-binding peritrophin-A domain (ChBD) and/or a low-density lipoprotein receptor class A domain (LDLa)
      cl02629
      Location:33 – 88
      Blast Score: 116
      CBM_14; Chitin binding Peritrophin-A domain
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    mRNA BT016093.1 AAV36978.1
    genomic AE014296.4 AAF49121.2
    genomic AE014296.4 AAN11656.1
    genomic AE014296.4 AAF49123.2
    genomic AE014296.4 ACZ94741.1
    genomic AE014296.4 AAF49122.1
    genomic AE014296.4 ACZ94740.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IQU1.1 GenPept
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    Additional Links

    Gene LinkOut

      Supplemental Content