These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
mRNA and Protein(s)
-
NM_005358.5 → NP_005349.3 LIM domain only protein 7 isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the predominant transcript and encodes isoform 1.
- Source sequence(s)
-
AA777749, AB020665, AF330045, AL137244, AW805522, DB064574
- Consensus CDS
-
CCDS9454.1
- UniProtKB/Swiss-Prot
-
Q8WWI1
- Related
- ENSP00000342112, OTTHUMP00000018512, ENST00000341547, OTTHUMT00000045297
- Conserved Domains (3) summary
-
- cd00014
Location:65 – 181
Blast Score: 155
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00136
Location:721 – 788
Blast Score: 154
- PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
- cd08368
Location:1280 – 1338
Blast Score: 152
- LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers.
-
NM_015842.2 → NP_056667.2 LIM domain only protein 7 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) is alternatively spliced at the 5' and 3' ends, and contains 2 additional internal in-frame coding exons, compared to transcript variant 1. This results in a longer isoform (2) with different N- and C- termini compared to isoform 1.
- Source sequence(s)
-
AA777749, AB020665, AF330045, AK055465, AW805522, DB064574, DB227898
- Consensus CDS
-
CCDS53876.1
- UniProtKB/TrEMBL
-
E9PLH4
- UniProtKB/Swiss-Prot
-
Q8WWI1
- Related
- ENSP00000433352, OTTHUMP00000232450, ENST00000465261, OTTHUMT00000045298
- Conserved Domains (1) summary
-
- cd00136
Location:770 – 837
Blast Score: 154
- PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000013.10 Reference GRCh37.p5 Primary Assembly
- Range
- 76194570..76434006
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000145.1 Alternate HuRef
- Range
- 56891721..57131153
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the cited
reason(s). Suppressed RefSeqs do not appear in BLAST databases, related sequence links,
or BLAST links (BLink), but may still be retrieved by clicking on their
accession.version below.
-
NM_015843.1: Suppressed sequence
- Description
- NM_015843.1: This RefSeq was temporarily suppressed because the CDS is 5'' partial, and currently there is not sufficient data to support this transcript variant.