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scnn1a.L sodium channel, non voltage gated 1 alpha subunit L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 397811, updated on 11-Apr-2024

Summary

Official Symbol
scnn1a.L
Official Full Name
sodium channel, non voltage gated 1 alpha subunit L homeolog
Primary source
Xenbase:XB-GENE-996110
Locus tag
XELAEV_18034427mg
See related
EnsemblRapid:ENSXLAG00005036580
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
besc2; enaca; scnn1; scnn1a; ENaCalpha; alphaxENaC
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Genomic context

Location:
chromosome: 7L
Exon count:
13
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7L NC_054383.1 (7963668..7990754)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7L NC_030736.1 (7993090..8020522)

Chromosome 7L - NC_054383.1Genomic Context describing neighboring genes Neighboring gene tapasin-related protein Neighboring gene lymphotoxin beta receptor L homeolog Neighboring gene TNF receptor superfamily member 1A L homeolog Neighboring gene U7 small nuclear RNA

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ligand-gated sodium channel activity IEA
Inferred from Electronic Annotation
more info
 
contributes_to ligand-gated sodium channel activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables sodium channel activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within multicellular organismal-level water homeostasis ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within sodium ion homeostasis ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within sodium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within sodium ion transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within sodium ion transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in acrosomal vesicle IEA
Inferred from Electronic Annotation
more info
 
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in apical plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in ciliary membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in motile cilium IEA
Inferred from Electronic Annotation
more info
 
located_in motile cilium ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of sodium channel complex IEA
Inferred from Electronic Annotation
more info
 
part_of sodium channel complex ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
amiloride-sensitive sodium channel subunit alpha
Names
SCNEA
alpha-ENaC
alpha-NaCH
epithelial Na(+) channel subunit alpha
epithelial sodium channel alpha subunit
nonvoltage-gated sodium channel 1 subunit alpha
sodium channel, non-voltage-gated 1 alpha subunit
sodium channel, nonvoltage-gated 1 alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001087923.1NP_001081392.1  amiloride-sensitive sodium channel subunit alpha

    See identical proteins and their annotated locations for NP_001081392.1

    Status: PROVISIONAL

    Source sequence(s)
    U23535
    UniProtKB/Swiss-Prot
    P51167
    UniProtKB/TrEMBL
    A0A974HB34, B7ZQR7
    Related
    ENSXLAP00005109461.1, ENSXLAT00005111663.1
    Conserved Domains (2) summary
    TIGR00859
    Location:18602
    ENaC; sodium channel transporter
    TIGR00867
    Location:26530
    deg-1; degenerin

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054383.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    7963668..7990754
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)