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OLR1 oxidized low density lipoprotein receptor 1 [ Sus scrofa (pig) ]

Gene ID: 396724, updated on 5-Mar-2024

Summary

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Official Symbol
OLR1provided by VGNC
Official Full Name
oxidized low density lipoprotein receptor 1provided by VGNC
Primary source
VGNC:VGNC:91038
See related
Ensembl:ENSSSCG00000000647
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
LOX1; OLR-1; CLEC8A; PLOX-1
Annotation information
Annotation category: partial on reference assembly
Expression
Broad expression in lung (RPKM 10.8), heart (RPKM 9.5) and 6 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
6
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 5 NC_010447.5 (61799356..61809691)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 5 NC_010447.4 (64580096..64590442, complement)

Chromosome 5 - NC_010447.5Genomic Context describing neighboring genes Neighboring gene GABA type A receptor associated protein like 1 Neighboring gene transmembrane protein 52B Neighboring gene C-type lectin domain containing 7A Neighboring gene C-type lectin domain family 1 member A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Conserved C-terminal residues within the lectin-like domain of LOX-1 are essential for oxidized low-density-lipoprotein binding. Chen M, et al. Biochem J, 2001 Apr 15. PMID 11284714, Free PMC Article
  2. Selective activation of lectin-like oxidized low-density lipoprotein receptor-1 mediates C-reactive protein-evoked endothelial vasodilator dysfunction in coronary arterioles. Hein TW, et al. Circ Res, 2014 Jan 3. PMID 24141169
  3. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  4. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables low-density lipoprotein particle receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell death IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in leukocyte cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipoprotein metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
oxidized low-density lipoprotein receptor 1
Names
C-type lectin domain family 8 member A
LOX-1
lectin-like oxLDL receptor 1
lectin-like oxidized LDL receptor-1
lectin-type oxidized LDL receptor 1
ox-LDL receptor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213805.1 → NP_998970.1  oxidized low-density lipoprotein receptor 1

    See identical proteins and their annotated locations for NP_998970.1

    Status: PROVISIONAL

    Source sequence(s)
    AB018668
    UniProtKB/Swiss-Prot
    Q9TTK7
    UniProtKB/TrEMBL
    A0A076KWW8, A0A0B8RZB2, A0A4X1V3B9, A0A8D0YMJ3, A8CVN6, F1SPE3
    Related
    ENSSSCP00000000683.2, ENSSSCT00000000698.4
    Conserved Domains (1) summary
    cd03593
    Location:144 → 266
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010447.5 Reference Sscrofa11.1 Primary Assembly

    Range
    61799356..61809691
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9TTK7.1 GenPept UniProtKB/Swiss-Prot:Q9TTK7

Gene LinkOut

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