NGF nerve growth factor (beta polypeptide) [Gallus gallus] - Gene

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Summary

Symbol: NGFprovided by CGNC
Full Name: nerve growth factor (beta polypeptide)provided by CGNC
Primary source: CGNC:1838
See related: Ensembl:ENSGALG00000002556
Gene type: protein coding
RefSeq status: MODEL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: NGFB

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Genomic context

Location :: chromosome: 26

Sequence :: Chromosome: 26; NC_006113.3 (3969392..3992367, complement)

See NGF in MapViewer

Chromosome 26 - NC_006113.3 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results reveal a role for NGF in early chicken embryo development.
Title: Nerve growth factor regulates axial rotation during early stages of chick embryo development.
Levels of NGF, BDNF and NT-3 were all up regulated from E7 to E14 in the spinal cord of embryonic chicken during development.
Title: [The expression level of NGF, BDNF and NT-3 in spinal cord of growing embryonic chicken].
Data show that endogenous NGF induces DNA replication in a subpopulation of differentiating retinal ganglion cells that express both the neurotrophin receptor p75 and the E2F1 transcription factor, but that lack the retinoblastoma protein.
Title: Somatic tetraploidy in specific chick retinal ganglion cells induced by nerve growth factor.
Transcripts of exon 1b are expressed in most tissues tested, whereas exon 1a are mainly in heart and reproductive organs and exon 1c are in peripheral organs other than heart.
Title: Alternative usage of 5' exons in the chicken nerve growth factor gene: refined characterization of a weakly expressed gene.

Submit: New GeneRIF Correction

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General gene information

Genotypes

Homology

Homologs of the NGF gene: The NGF gene is conserved in human, chimpanzee, , dog, cow, mouse, and rat.

Pathways from BioSystems

Apoptosis, organism-specific biosystem (from KEGG)
Apoptosis, organism-specific biosystemApoptosis is a genetically controlled mechanisms of cell death involved in the regulation of tissue homeostasis. The 2 major pathways of apoptosis are the extrinsic (Fas and other TNFR superfamily me...
Apoptosis, conserved biosystem (from KEGG)
Apoptosis, conserved biosystemApoptosis is a genetically controlled mechanisms of cell death involved in the regulation of tissue homeostasis. The 2 major pathways of apoptosis are the extrinsic (Fas and other TNFR superfamily me...
Id Signaling Pathway, organism-specific biosystem (from WikiPathways)
Id Signaling Pathway, organism-specific biosystemInhibitor of DNA binding (ID) proteins are members of the helix-loop-helix (HLH) family of proteins which lack a DNA binding domain themselves but bind to other family members inhibiting their DNA bi...
MAPK signaling pathway, organism-specific biosystem (from WikiPathways)
MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
MAPK signaling pathway, organism-specific biosystem (from KEGG)
MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
MAPK signaling pathway, conserved biosystem (from KEGG)
MAPK signaling pathway, conserved biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
growth factor activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
extracellular region	IEA Inferred from Electronic Annotation more info

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General protein information

Preferred Names: beta-nerve growth factor

Names: nerve growth factor (beta polypeptide); beta-NGF; beta-nerve growth factor; nerve growth factor, beta polypeptide

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NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Build 3.1

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Gallus_gallus-4.0 Primary Assembly

Genomic

NC_006113.3

Range

3969392..3992367, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_003642729.1 → XP_003642777.1

Conserved Domains (1) summary

cl02481
Location:124 – 238
Blast Score: 570

NGF; Nerve growth factor family
XM_418016.3 → XP_418016.3

Conserved Domains (1) summary

cl02481
Location:124 – 238
Blast Score: 570

NGF; Nerve growth factor family