U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Neurl4 Neuralized E3 ubiquitin protein ligase 4 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39558, updated on 27-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Neurl4provided by FlyBase
Official Full Name
Neuralized E3 ubiquitin protein ligase 4provided by FlyBase
Primary source
FLYBASE:FBgn0283503
Locus tag
Dmel_CG46284
See related
AllianceGenome:FB:FBgn0283503
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
blue; Blue; CG46284; CG6451; Dmel\CG46284
Summary
Located in centrosome. Orthologous to human NEURL4 (neuralized E3 ubiquitin protein ligase 4). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
70C15-70D1; 3-41 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (14043694..14049892, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (14036794..14042992, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR42871 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Heat shock protein 110 Neighboring gene antisense RNA:CR46067 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Formin-like

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Neurl4 contributes to germ cell formation and integrity in Drosophila. Jones J, et al. Biol Open, 2015 Jun 26. PMID 26116656, Free PMC Article
  2. Unique and Overlapping Functions of Formins Frl and DAAM During Ommatidial Rotation and Neuronal Development in Drosophila. Dollar G, et al. Genetics, 2016 Mar. PMID 26801180, Free PMC Article
  3. The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway. Imai Y, et al. PLoS Genet, 2015 Sep. PMID 26355680, Free PMC Article
  4. DNA supercoiling factor contributes to dosage compensation in Drosophila. Furuhashi H, et al. Development, 2006 Nov. PMID 17035293
  5. Population-scale long-read sequencing uncovers transposable elements associated with gene expression variation and adaptive signatures in Drosophila. Rech GE, et al. Nat Commun, 2022 Apr 12. PMID 35413957, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in centrosome IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
neuralized E3 ubiquitin protein ligase 4
Names
CG46284-PA
Neurl4-PA

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    14043694..14049892 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140431.3 → NP_648688.2  neuralized E3 ubiquitin protein ligase 4 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648688.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1L4AAD6, Q32KB8
    Related
    FBpp0401556
    Conserved Domains (2) summary
    smart00588
    Location:221 → 345
    NEUZ; domain in neuralized proteins
    cd12887
    Location:467 → 629
    SPRY_NHR_like; SPRY domain in neuralized homology repeat
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A1L4AAD6 A0A1L4AAD6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous