ATM ataxia telangiectasia mutated [Gallus gallus] - Gene

Help top of page

Summary

Symbol: ATMprovided by CGNC
Full Name: ataxia telangiectasia mutatedprovided by CGNC
Primary source: CGNC:12888
See related: Ensembl:ENSGALG00000017159
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus

Help top of page

Genomic context

Location :: chromosome: 1

Sequence :: Chromosome: 1; NC_006088.3 (179508592..179568303, complement)

See ATM in MapViewer

Chromosome 1 - NC_006088.3 Genomic Context describing neighboring genes

Help top of page

Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

Help top of page

Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

Help top of page

General gene information

Homology

Homologs of the ATM gene: The ATM gene is conserved in human, chimpanzee, , dog, cow, mouse, rat, and zebrafish.

Pathways from BioSystems

Apoptosis, organism-specific biosystem (from KEGG)
Apoptosis, organism-specific biosystemApoptosis is a genetically controlled mechanisms of cell death involved in the regulation of tissue homeostasis. The 2 major pathways of apoptosis are the extrinsic (Fas and other TNFR superfamily me...
Apoptosis, conserved biosystem (from KEGG)
Apoptosis, conserved biosystemApoptosis is a genetically controlled mechanisms of cell death involved in the regulation of tissue homeostasis. The 2 major pathways of apoptosis are the extrinsic (Fas and other TNFR superfamily me...
BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem (from KEGG)
BRCA1-associated genome surveillance complex (BASC), organism-specific biosystemStructural complex; Genetic information processing; Repair system
Cell cycle, organism-specific biosystem (from KEGG)
Cell cycle, organism-specific biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps known as G1 and G2 phases. Cycli...
Cell cycle, conserved biosystem (from KEGG)
Cell cycle, conserved biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps known as G1 and G2 phases. Cycli...
G1 to S cell cycle control, organism-specific biosystem (from WikiPathways)
G1 to S cell cycle control, organism-specific biosystemIn the G1 phase there are two types of DNA damage responses, the p53-dependent and the p53-independent pathways. The p53-dependent responses inhibit CDKs through the up-regulation of genes encoding C...
Ovarian Infertility Genes, organism-specific biosystem (from WikiPathways)
Ovarian Infertility Genes, organism-specific biosystemOvarian ???bottleneck??? genes associated with infertility A valuable approach to the study of infertility is the comparison of mutations of individual human and mouse genes associated with infertili...
p53 signaling pathway, organism-specific biosystem (from KEGG)
p53 signaling pathway, organism-specific biosystemp53 activation is induced by a number of stress signals, including DNA damage, oxidative stress and activated oncogenes. The p53 protein is employed as a transcriptional activator of p53-regulated ge...
p53 signaling pathway, conserved biosystem (from KEGG)
p53 signaling pathway, conserved biosystemp53 activation is induced by a number of stress signals, including DNA damage, oxidative stress and activated oncogenes. The p53 protein is employed as a transcriptional activator of p53-regulated ge...

Help top of page

General protein information

Preferred Names: serine-protein kinase ATM

Names: serine-protein kinase ATM; ATM (ataxia telangiectasia mutated); ataxia telangiectasia mutated (includes complementation groups A, C and D)

NP_001155872.1

EC 2.7.11.1

Help top of page

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001162400.1 → NP_001155872.1 serine-protein kinase ATM

Status: PROVISIONAL

Source sequence(s)

AADN02005056, AADN02005057, AADN02005058

Conserved Domains (5) summary

cd05171
Location:2677 – 2956
Blast Score: 1468

PIKKc_ATM; Ataxia telangiectasia mutated (ATM), catalytic domain; The ATM catalytic domain subfamily is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein kinases (PKs), ...

smart00146
Location:2709 – 2958
Blast Score: 684

PI3Kc; Phosphoinositide 3-kinase, catalytic domain

pfam02259
Location:2090 – 2483
Blast Score: 491

FAT; FAT domain

pfam02260
Location:3020 – 3049
Blast Score: 139

FATC; FATC domain

pfam11640
Location:6 – 164
Blast Score: 261

TAN; Telomere-length maintenance and DNA damage repair

RefSeqs of Annotated Genomes: Build 3.1

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Gallus_gallus-4.0 Primary Assembly

Genomic

NC_006088.3 Reference Gallus_gallus-4.0 Primary Assembly

Range

179508592..179568303, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)