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    CG8745 [ Drosophila melanogaster ]

    Gene ID: 39530, updated on 10-May-2012
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    Summary

    Official Symbol
    CG8745provided by Flybase
    Primary source
    FLYBASE:FBgn0036381
    Locus tag
    Dmel_CG8745
    Gene type
    protein coding
    RNA name
    CG8745
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8745
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    Genomic context

    Location :
    70C5-70C5
    Sequence :
    Chromosome: 3L; NT_037436.3 (13853102..13859985, complement)
    See CG8745 in Epigenomics, MapViewer

    Chromosome 3L - NT_037436.3Genomic Context describing neighboring genes Neighboring gene CG8750 gene product from transcript CG8750-RA Neighboring gene Tetraspanin 68C Neighboring gene Hemolectin Neighboring gene CG32132 gene product from transcript CG32132-RA Neighboring gene CG34400 gene product from transcript CG34400-RD Neighboring gene CG13737 gene product from transcript CG13737-RA

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573.
    2. Dissecting differential gene expression within the circadian neuronal circuit of Drosophila. Nagoshi E, et al. Nat Neurosci, 2010 Jan. PMID 19966839.
    3. Elevation of glutamine level by selenophosphate synthetase 1 knockdown induces megamitochondrial formation in Drosophila cells. Shim MS, et al. J Biol Chem, 2009 Nov 20. PMID 19755423.
    4. Somatic, germline and sex hierarchy regulated gene expression during Drosophila metamorphosis. Lebo MS, et al. BMC Genomics, 2009 Feb 13. PMID 19216785.
    5. Nodal points and complexity of Notch-Ras signal integration. Hurlbut GD, et al. Proc Natl Acad Sci U S A, 2009 Feb 17. PMID 19171888.

    See all (16) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:64872 BioGRID:61554 CG1620    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:64872 BioGRID:58064 CG3847    BioGRID  PubMed Two-hybrid 
    BioGRID:64872 BioGRID:60729 CG5792    BioGRID  PubMed Two-hybrid 
    BioGRID:64872 BioGRID:60168 CG5973    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:64872 BioGRID:62275 CG6220    BioGRID  PubMed Two-hybrid 
    BioGRID:64872 BioGRID:65636 CG7173    BioGRID  PubMed Two-hybrid 
    BioGRID:64872 BioGRID:62988 DMAP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:64872 BioGRID:57914 HLH4C    BioGRID  PubMed Two-hybrid 
    BioGRID:64872 BioGRID:62728 Mapmodulin    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:64872 BioGRID:61720 MrgBP    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:64872 BioGRID:64037 Rpd3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:64872 BioGRID:63374 TBPH    BioGRID  PubMed Two-hybrid 
    BioGRID:64872 BioGRID:69802 dom    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:64872 BioGRID:72727 pont    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:64872 BioGRID:65368 rept    BioGRID  PubMed Affinity Capture-MS 
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    General gene information

    Homology

    • Homologs of the CG8745 gene: The CG8745 gene is conserved in human, chimpanzee, , dog, cow, mouse, chicken, zebrafish, mosquito, and C.elegans.

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    alanine-glyoxylate transaminase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    ornithine-oxo-acid transaminase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    arginine catabolic process to glutamate ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
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    General protein information

    Preferred Names
    CG8745 gene product from transcript CG8745-RA
    Names
    CG8745
    CG8745-PA
    NP_648665.1
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.3

      Range
      13853102..13859985, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140408.2 → NP_648665.1  CG8745 [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VU95
      Related
      FBpp0075543, FBtr0075801
      Conserved Domains (2) summary
      COG0160
      Location:20 – 450
      Blast Score: 1072
      GabT; 4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]
      cd00610
      Location:37 – 447
      Blast Score: 1136
      OAT_like; Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase, ...
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    mRNA AY061111.1 AAL28659.1
    genomic AE014296.4 AAF49794.2
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VU95.2 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

      Supplemental Content