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    CG10754 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39456, updated on 9-Jun-2013
    Official Symbol
    CG10754provided by FlyBase
    Primary source
    FLYBASE:FBgn0036314
    Locus tag
    Dmel_CG10754
    Gene type
    protein coding
    RNA name
    CG10754
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10754
    Location :
    69E4-69E4
    Sequence :
    Chromosome: 3L; NT_037436.3 (12806128..12807119, complement)
    See CG10754 in Epigenomics, MapViewer

    Chromosome 3L - NT_037436.3Genomic Context describing neighboring genes Neighboring gene Autophagy-specific gene 1 Neighboring gene CG42709 gene product from transcript CG42709-RA Neighboring gene Sin3A-associated protein 130 Neighboring gene CG32110 gene product from transcript CG32110-RA Neighboring gene CG42588 gene product from transcript CG42588-RA Neighboring gene CG10960 gene product from transcript CG10960-RC

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573.
    2. Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi. Neumüller RA, et al. Cell Stem Cell, 2011 May 6. PMID 21549331.
    3. Quantitative trait loci for aggressive behavior in Drosophila melanogaster. Edwards AC, et al. Genetics, 2009 Jul. PMID 19414563.
    4. Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Herold N, et al. Mol Cell Biol, 2009 Jan. PMID 18981222.
    5. Identification of Drosophila mitotic genes by combining co-expression analysis and RNA interference. Somma MP, et al. PLoS Genet, 2008 Jul 18. PMID 18797514.

    See all (17) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction
    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:64803 BioGRID:67089 CG16941    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:64803 BioGRID:68233 CG5514    BioGRID  PubMed Two-hybrid 
    BioGRID:64803 BioGRID:63929 dar1    BioGRID  PubMed Two-hybrid 
    BioGRID:64803 BioGRID:65884 noi    BioGRID  PubMed Affinity Capture-MS 

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    mRNA splicing, via spliceosome IC
    Inferred by Curator
    more info
    		 PubMed 
    mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    mitotic spindle organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    neurogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		  
    Component Evidence Code Pubs
    U2 snRNP ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    catalytic step 2 spliceosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    precatalytic spliceosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    spliceosomal complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Preferred Names
    CG10754 gene product from transcript CG10754-RA
    Names
    CG10754
    CG10754-PA

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.3

      Range
      12806128..12807119, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140346.2 → NP_648603.1  CG10754 [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VU15
      Related
      FBpp0075676, FBtr0075944
      Conserved Domains (3) summary
      COG5246
      Location:1 – 214
      Blast Score: 515
      PRP11; Splicing factor 3a, subunit 2 [RNA processing and modification]
      smart00451
      Location:52 – 82
      Blast Score: 106
      ZnF_U1; U1-like zinc finger
      cl10717
      Location:100 – 214
      Blast Score: 295
      CactinC_cactus; Cactus-binding C-terminus of cactin protein
    Nucleotide Protein
    Heading Accession and Version
    mRNA AY118970.1 AAM50830.1
    genomic AE014296.4 AAF49876.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VU15.1 GenPept

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

      Table of contents

      Related information

      • BioAssay
        Related PubChem BioAssays
      • BioAssays, RNAi Target,Active
        BioAssays, RNAi Target,Active
      • BioProjects
        BioProjects related to a gene
      • BioSystems
        BioSystems
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • Full text in PMC
        PMC links
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • Genome
        Genome records having the gene annotated on corresponding genomic reference sequence.
      • GEO Profiles
        Related GEO
      • HomoloGene
        Links between HomoloGene and Gene are provided by the HomoloGene group when a gene is included in a HomoloGene record.
      • Map Viewer
        These links are maintained by the Map Viewer group and are provided when a GeneID is annotated on a map for the same species.
      • Nucleotide
        Link to related Nucleotide entry
      • Probe
        Related Probe entry
      • Protein
        Link to related protein entry
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed (GeneRIF)
        GeneRIF -- Gene Reference Into Function Staff of the Index Section in the National Library of Medicine review the current literature. When they find articles focused on the structure and function of a gene, they write a brief summary of the impact of the paper and make the connection between the citation (PubMed) and Gene. An interface exists for interested users to submit such data as well. http://www.ncbi.nlm.nih.gov/projects/GeneRIF/GeneRIFhelp.html
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • Taxonomy
        Link to related taxonomy entry
      • UniGene
        Links are provided between Gene and UniGene when both databases calculate links to the same mRNA record (gi).

      Links to other resources

      General information

      Related sites

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